3-[(1E)-1-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}ethyl]-5-[3-(trifluoromethyl)phenyl]-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione CAS 339276-47-0
| CAS No. | 339276-47-0 |
| Molecular Formula | C20H12ClF6N5O3 |
| Molecular Weight | 519.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-[(1E)-1-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}ethyl]-5-[3-(trifluoromethyl)phenyl]-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-[(1E)-1-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}ethyl]-5-[3-(trifluoromethyl)phenyl]-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 339276-47-0), molecular formula C20H12ClF6N5O3 and molecular weight 519.78 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 3-[(1E)-1-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}ethyl]-5-[3-(trifluoromethyl)phenyl]-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 519.78 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H12ClF6N5O3 |
| Molecular Weight | 519.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related E Standards
- 4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-6-hydroxy-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyrimidin-2-one (CAS 339012-76-9)
- 1-[(5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophen-2-yl)sulfonyl]-4-(4-fluorophenyl)piperazine (CAS 337924-67-1)
- N-(5-Chloro-2-methoxyphenyl)-2-((4-(2-chlorophenyl)-3-cyano-6-phenylpyridin-2-yl)thio)acetamide (CAS 332164-03-1)
- 4-(((4-(5-Chloro-2-(((1S,4r)-4-(((S)-1-methoxypropan-2-yl)amino)cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (CAS 2247481-22-5)
- 7-Chloro-3-(3,4-dichlorophenyl)-1-((1-ethylpiperidin-3-yl)imino)-10-hydroxy-1,2,3,4-tetrahydroacridin-9(10H)-one (CAS 144128-42-7)
- 3-{2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]pyridin-3-yl}-1-[3-(trifluoromethyl)phenyl]urea (CAS 338772-83-1)
- 4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}-N-(2,3,4,5,6-pentafluorophenyl)benzene-1-sulfonamide (CAS 338775-47-6)
- N-{2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]-5-(trifluoromethyl)phenyl}-4-fluorobenzamide (CAS 478262-28-1)
Recommended Standards
- 5'-(4-Amino-3,5-diethylphenyl)-3,3'',5,5''-tetraethyl-[1,1':3',1''-terphenyl]-4,4''-diamine (CAS 2250216-97-6)
- 4-((3,5-Bis(trifluoromethyl)phenoxy)methyl)-5-(chloromethyl)-2-(4-(trifluoromethyl)phenyl)thiazole (CAS 1365033-43-7)
- (Z)-(2-(benzo[d][1,3]dioxol-5-yl)cyclopropyl)(4-chloro-3-nitrophenyl)methanone O-(2,4-dichlorobenzyl) oxime (CAS 338749-00-1)
- 2-((4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dichlorophenyl)acetamide (CAS 476484-43-2)
- Perbromocyclopenta-1,3-diene (CAS 14310-17-9)
- 2-(Spiro[3.3]Heptan-2-yl)ethan-1-ol (CAS 3617-81-0)
- 1-Cyclopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid (CAS 773098-78-5)
- Dinonyl sebacate (CAS 4121-16-8)
- 2-Chloro-n'-(2-chlorobenzoyl)benzohydrazide (CAS 38192-13-1)
- 8-(1H-Imidazol-1-yl)-2-methyl-3-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidine (CAS 896838-67-8)
- 6-Formyl-2,3-dihydroxybenzoic acid (CAS 22231-81-8)
- Methyl 2-formyl-5-isopropylbenzoate (CAS 2624417-55-4)
- Methyl 4-amino-4-(5-methylthiophen-2-yl)butanoate (CAS 1218596-86-1)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
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