4-(3-(2,2,2-Trifluoroacetamido)propyl)benzenesulfonyl chloride CAS 477259-57-7

Purity 97%+In StockPharmaceutical Standards
CAS No.477259-57-7
Molecular FormulaC11H11ClF3NO3S
Molecular Weight329.72 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(3-(2,2,2-Trifluoroacetamido)propyl)benzenesulfonyl chloride CAS 477259-57-7 chemical structure

Description

4-(3-(2,2,2-Trifluoroacetamido)propyl)benzenesulfonyl chloride (CAS 477259-57-7) is a high-purity analytical reference standard with the molecular formula C11H11ClF3NO3S and a molecular weight of 329.72 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 4-(3-(2,2,2-Trifluoroacetamido)propyl)benzenesulfonyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 329.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(3-(2,2,2-Trifluoroacetamido)propyl)benzenesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H11ClF3NO3S
Molecular Weight329.72 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms1
Sulfur Atoms1

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