5-(2,2,2-Trifluoroacetamido)naphthalene-1-sulfonyl chloride CAS 160206-27-9

Purity 97%+In StockPharmaceutical Standards
CAS No.160206-27-9
Molecular FormulaC12H7ClF3NO3S
Molecular Weight337.70 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(2,2,2-Trifluoroacetamido)naphthalene-1-sulfonyl chloride CAS 160206-27-9 chemical structure

Description

The occurrence of 5-(2,2,2-Trifluoroacetamido)naphthalene-1-sulfonyl chloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-(2,2,2-Trifluoroacetamido)naphthalene-1-sulfonyl chloride (CAS 160206-27-9), molecular formula C12H7ClF3NO3S and molecular weight 337.70 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-(2,2,2-Trifluoroacetamido)naphthalene-1-sulfonyl chloride (C12H7ClF3NO3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures 5-(2,2,2-Trifluoroacetamido)naphthalene-1-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H7ClF3NO3S
Molecular Weight337.70 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2002
Halogen ContentF/Cl-containing
Nitrogen Atoms1
Sulfur Atoms1

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