3-((5-Chloro-2-methoxyphenyl)amino)-1-(p-tolyl)propan-1-one CAS 477328-95-3

Purity 97%+In StockPharmaceutical Standards
CAS No.477328-95-3
Molecular FormulaC17H18ClNO2
Molecular Weight303.78 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-((5-Chloro-2-methoxyphenyl)amino)-1-(p-tolyl)propan-1-one CAS 477328-95-3 chemical structure

Description

3-((5-Chloro-2-methoxyphenyl)amino)-1-(p-tolyl)propan-1-one (CAS 477328-95-3) is a high-purity analytical reference standard with the molecular formula C17H18ClNO2 and a molecular weight of 303.78 g/mol.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 3-((5-Chloro-2-methoxyphenyl)amino)-1-(p-tolyl)propan-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 303.78 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-((5-Chloro-2-methoxyphenyl)amino)-1-(p-tolyl)propan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H18ClNO2
Molecular Weight303.78 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms1

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