N-(4-(Benzo[d]oxazol-2-yl)phenyl)-5-chlorothiophene-2-carboxamide CAS 477503-79-0

Purity 97%+In StockPharmaceutical Standards
CAS No.477503-79-0
Molecular FormulaC18H11ClN2O2S
Molecular Weight354.81 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-(Benzo[d]oxazol-2-yl)phenyl)-5-chlorothiophene-2-carboxamide CAS 477503-79-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 354.81 g/mol gives N-(4-(Benzo[d]oxazol-2-yl)phenyl)-5-chlorothiophene-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies N-(4-(Benzo[d]oxazol-2-yl)phenyl)-5-chlorothiophene-2-carboxamide (CAS 477503-79-0), a certified reference material (molecular formula C18H11ClN2O2S, MW 354.81 g/mol) for analytical method development and quality control.

The molecular framework of N-(4-(Benzo[d]oxazol-2-yl)phenyl)-5-chlorothiophene-2-carboxamide (C18H11ClN2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(4-(Benzo[d]oxazol-2-yl)phenyl)-5-chlorothiophene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H11ClN2O2S
Molecular Weight354.81 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

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