1-(4-(3-Nitrophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid CAS 477708-91-1
| CAS No. | 477708-91-1 |
| Molecular Formula | C14H7F3N4O4S |
| Molecular Weight | 384.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 384.29 g/mol gives 1-(4-(3-Nitrophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(4-(3-Nitrophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 477708-91-1) is a high-purity analytical reference standard with the molecular formula C14H7F3N4O4S and a molecular weight of 384.29 g/mol.
1-(4-(3-Nitrophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (C14H7F3N4O4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(4-(3-Nitrophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H7F3N4O4S |
| Molecular Weight | 384.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Nitrophenyl Standards
- 1-Benzyl 2-(4-nitrophenyl) (S)-5-oxopyrrolidine-1,2-dicarboxylate (CAS 40356-52-3)
- 4-Nitrophenyl 2-acetamido-3-O-acetyl-2-deoxy-β-D-glucopyranoside (CAS 23262-57-9)
- 2,5-Bis(4-nitrophenyl)thiazolo[5,4-d]thiazole (CAS 4402-40-8)
- 1-(5-(3-Nitrophenyl)-1-tosyl-1H-pyrrol-2-yl)ethan-1-one (CAS 827024-09-9)
- 2-{2-[4-(3-nitrophenyl)piperazin-1-yl]ethyl}-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one (CAS 1263386-35-1)
- 2-((4-(3-Nitrophenyl)thiazol-2-yl)amino)-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 866142-60-1)
- N-(2-nitrophenyl)-2-(4-(4-nitrophenyl)piperazin-1-yl)acetamide (CAS 882080-67-3)
- 1-(4-Nitrophenyl)-3-[3-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea (CAS 2096998-08-0)
Recommended Standards
- 4-Bromo-N-(4-methoxybenzyl)-2,6-dimethylbenzenesulfonamide (CAS 1704096-07-0)
- 2-((4-Amino-5-(tert-butyl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-bromophenyl)acetamide (CAS 540498-84-8)
- 4-((1H-Imidazol-1-yl)methyl)-1-((4-bromophenyl)sulfonyl)piperidine (CAS 1396872-95-9)
- N-[4-(2,4-Dichlorophenoxy)butyl]-3-(2-methoxyethoxy)aniline (CAS 1040686-27-8)
- Ethyl 3-bromo-7-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylate (CAS 1419101-12-4)
- 4,6-Dichloro-2-methyl-5-phenylnicotinonitrile (CAS 127581-38-8)
- 3-[(3-Amino-1-piperidinyl)methyl]phenol dihydrochloride (CAS 1158446-46-8)
- tert-Butyl (6-((6-aminohexyl)(methyl)amino)hexyl)carbamate (CAS 2665659-91-4)
- 4-(4-Bromophenyl)-1-methyl-1,4-azaphosphinane 4-oxide (CAS 2685825-13-0)
- N-Benzyl-5-bromo-1-benzothiophene-2-carboxamide (CAS 439108-01-7)
- Methyl 6-Amino-1,3-benzothiazole-2-carboxylate (CAS 1048367-37-8)
- 5-Formyl-1-methyl-1H-pyrazole-3-carboxylic acid (CAS 221323-55-3)
- 3-(3,5-Dimethoxyphenyl)-1h-1,2,4-triazol-5-amine (CAS 312920-26-6)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com