3-(2-Amino-6-chloropyrimidin-4-yl)-[1,1'-biphenyl]-4,4'-diol CAS 477726-63-9
| CAS No. | 477726-63-9 |
| Molecular Formula | C16H12ClN3O2 |
| Molecular Weight | 313.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2-Amino-6-chloropyrimidin-4-yl)-[1,1'-biphenyl]-4,4'-diol (C16H12ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-(2-Amino-6-chloropyrimidin-4-yl)-[1,1'-biphenyl]-4,4'-diol (CAS 477726-63-9), molecular formula C16H12ClN3O2 and molecular weight 313.74 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12ClN3O2 |
| Molecular Weight | 313.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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- Ammonium 2-(ethoxycarbonyl)benzenesulfonate (CAS 164078-39-1)
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- 4-((3-Bromophenoxy)methyl)tetrahydro-2H-pyran (CAS 1251337-10-6)
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- 1-Amino-7-bromo-2,3-dihydro-1H-indene (CAS 1071449-08-5)
- Q-Peptide trifluoroacetate salt (CAS 1361235-89-3)
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