2-{4-[5-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}acetonitrile CAS 477762-63-3
| CAS No. | 477762-63-3 |
| Molecular Formula | C16H16Cl2N4 |
| Molecular Weight | 335.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-{4-[5-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}acetonitrile is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-{4-[5-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}acetonitrile (CAS 477762-63-3), a certified reference material (molecular formula C16H16Cl2N4, MW 335.23 g/mol) for analytical method development and quality control.
Structurally, 2-{4-[5-(2,4-dichlorophenyl)-1H-pyrazol-3-yl]piperidin-1-yl}acetonitrile (C16H16Cl2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 335.23 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H16Cl2N4 |
| Molecular Weight | 335.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related dichlorophenyl Standards
- N-(2,3-Dichlorophenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142200-25-6)
- N-(2,4-Dichlorophenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142200-26-7)
- N-(2,5-Dichlorophenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142200-28-9)
- N-(3,4-Dichlorophenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142200-30-3)
- N-(3,5-Dichlorophenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142200-32-5)
- (S)-2-(2,6-dichlorophenyl)-1-((S)-1-phenylethyl)imidazolidin-4-one (CAS 1149765-12-7)
- (2R)-(2,6-Dichlorophenyl)-1-((1R)-1-phenylethyl)tetrahydro-1H-imidazol-4-one (CAS 1149765-13-8)
- (4-(3,4-Dichlorophenyl)piperazin-1-yl)(phenyl)methanone (CAS 866150-40-5)
Recommended Standards
- 2,4-Dichloro-N-[4-(pyrrolidin-1-yl)phenyl]benzamide (CAS 251097-22-0)
- 3-(3,4-Dichlorobenzyl)-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one (CAS 866043-33-6)
- 2-((5-Amino-1,3,4-thiadiazol-2-yl)thio)-N-(2,3-dichlorophenyl)acetamide (CAS 481691-44-5)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(2-methoxyphenyl)thiazol-5-yl)boronate (CAS 2223031-33-0)
- 2,2',2''-(2,4,6-Trimethylbenzene-1,3,5-triyl)triacetonitrile (CAS 16144-65-3)
- 2-Amino-6,7-dihydro-5H-pyrano[2,3-d]pyrimidine (CAS 88696-61-1)
- 5-Bromo-1-methyl-2,3-dihydro-1H-inden-1-amine hydrochloride (CAS 1447606-72-5)
- Pyridoxine impurity 85 (CAS CATO-C4X-187785)
- 2-(3-(tert-Butyl)phenyl)oxazolo[4,5-b]pyridine (CAS 60772-66-9)
- 2-Chloro-3-((2,2,2-trifluoroethyl)amino)naphthalene-1,4-dione (CAS 866008-04-0)
- (S)-3-(1-Amino-2,2,2-trifluoroethyl)benzoic acid hydrochloride (CAS 1391384-65-8)
- 7-Bromo-6-fluoro-1(2H)-isoquinolinone (CAS 923022-43-9)
- (3S,4S,5S)-3-Amino-5-(hydroxymethyl)-4-methyldihydrofuran-2(3H)-one (CAS 739322-12-4)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com