3-Chloro-2-(4-(3-(thiophen-2-yl)-1H-pyrazol-5-yl)piperidin-1-yl)-5-(trifluoromethyl)pyridine CAS 477762-67-7
| CAS No. | 477762-67-7 |
| Molecular Formula | C18H16ClF3N4S |
| Molecular Weight | 412.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Chloro-2-(4-(3-(thiophen-2-yl)-1H-pyrazol-5-yl)piperidin-1-yl)-5-(trifluoromethyl)pyridine.
CATO supplies 3-Chloro-2-(4-(3-(thiophen-2-yl)-1H-pyrazol-5-yl)piperidin-1-yl)-5-(trifluoromethyl)pyridine (CAS 477762-67-7), a certified reference material (molecular formula C18H16ClF3N4S, MW 412.86 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, 3-Chloro-2-(4-(3-(thiophen-2-yl)-1H-pyrazol-5-yl)piperidin-1-yl)-5-(trifluoromethyl)pyridine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 412.86 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Chloro-2-(4-(3-(thiophen-2-yl)-1H-pyrazol-5-yl)piperidin-1-yl)-5-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16ClF3N4S |
| Molecular Weight | 412.86 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-[(5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)formamido]-N-(4-methoxyphenyl)-2-phenylacetamide (CAS 1031210-14-6)
- 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-N,N-diethylthiophene-2-sulfonamide (CAS 344278-38-2)
- 1-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-N-(2-fluorobenzyl)pyrrolidine-2-carboxamide (CAS 1008011-41-3)
- 3-(2-Chloro-4-fluorobenzyl)-5-(6-methoxynaphthalen-2-yl)-5-methylimidazolidine-2,4-dione (CAS 956782-57-3)
- (E)-4-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)phenoxy)-1-(dimethylamino)pent-1-en-3-one (CAS 338416-09-4)
- 2-{[5-(6-chloro-3-pyridyl)-4-methyl-4H-1,2,4-triazol-3-yl]thio}-1-[3-(trifluoromethyl)phenyl]ethan-1-one (CAS 680217-47-4)
- 5-[(2-Chloro-6-fluorophenyl)methyl]-3-(trifluoromethyl)-5H,6H,6aH,7H,8H,9H,10H-pyrido[1,2-a]quinoxalin-6-one (CAS 1008229-49-9)
- 1-Chloro-9,10-bis(phenylethynyl)anthracene (CAS 41105-35-5)
Recommended Standards
- 2-{[(4-chlorophenyl)methyl]sulfanyl}-1-[4-(trifluoromethyl)benzoyl]-1,4,5,6-tetrahydropyrimidine (CAS 866153-37-9)
- Cefdinir Impurity 86 (CAS 1884263-19-7)
- (3,4-Bis((trimethylsilyl)ethynyl)hexa-3-en-1,5-diyne-1,6-diyl)bis(trimethylsilane) (CAS 55660-76-9)
- 2-(4-chlorophenoxy)-N-(3,4-dimethoxyphenethyl)nicotinamide (CAS 1023488-61-0)
- 3-(3,5-Dimethyl-1H-pyrazol-1-yl)propan-1-amine dihydrochloride (CAS 1185293-71-3)
- 424789-76-4 1-[1-(Benzenesulfonyl)-1H-indol-3-yl]-2-chloroethan-1-one DTXSID00573825 (CAS 424789-76-4)
- 4-((4-Bromobenzylidene)amino)-3-(3-ethoxyphenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 613249-70-0)
- [Dicyclohexyl[2′,4′,6′-tris(1-methylethyl)[1,1′-biphenyl]-2-yl]phosphine](4,5-dihydro-2-propyl-3-furanyl)gold (CAS 1426438-09-6)
- Cefcapene Impurity 19 (CAS CATO-C4X-182419)
- Dermorphin Trifluoroacetic Acid Salt (CAS 78331-26-7)
- 3-Aminochroman-6-carbonitrile (CAS 939758-96-0)
- N1,N1,N3,N3-Tetraethylmalonamide (CAS 33931-42-9)
- 6,8-Difluoro-4-methylumbelliferyl beta-D-glucopyranoside, 98% (CAS 351009-26-2)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
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