N-(4-bromophenyl)-1-(2-chlorobenzyl)-5-oxopyrrolidine-2-carboxamide CAS 477768-27-7
| CAS No. | 477768-27-7 |
| Molecular Formula | C18H16BrClN2O2 |
| Molecular Weight | 407.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(4-bromophenyl)-1-(2-chlorobenzyl)-5-oxopyrrolidine-2-carboxamide (C18H16BrClN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
N-(4-bromophenyl)-1-(2-chlorobenzyl)-5-oxopyrrolidine-2-carboxamide (CAS 477768-27-7), molecular formula C18H16BrClN2O2 and molecular weight 407.69 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(4-bromophenyl)-1-(2-chlorobenzyl)-5-oxopyrrolidine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16BrClN2O2 |
| Molecular Weight | 407.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- N-(2-Bromophenyl)-1-[(2-chlorophenyl)methyl]-5-oxopyrrolidine-2-carboxamide (CAS 1008658-26-1)
- 1-(4-Bromophenyl)-3-(4-(3-chlorophenyl)piperazin-1-yl)propan-1-one (CAS 952182-60-4)
- 2-(4-Bromophenyl)-5-chloro-4-(4-methoxyphenoxy)-2,3-dihydropyridazin-3-one (CAS 551921-42-7)
- N-(4-Bromophenyl)-2-((4-(piperidin-1-yl)pyrimidin-2-yl)thio)acetamide (CAS 1251707-34-2)
- 2-(4-Bromophenyl)-7-(methylsulfonyl)benzo[d]imidazo[2,1-b]thiazole (CAS 866135-76-4)
- (Z)-3-((4-Bromophenyl)(4-(methylsulfonyl)phenyl)methylene)dihydrofuran-2(3H)-one (CAS 197438-73-6)
- 4-((4-Bromophenyl)sulfonyl)-N-methyl-2-(o-tolyl)oxazol-5-amine (CAS 478171-37-8)
- N-(2-Bromophenyl)-2-((4-ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618413-46-0)
Recommended Standards
- Di-tert-butyl (6-bromo-5-chloropyridin-2-yl)iminodicarbonate (CAS 1492029-02-3)
- N-(5-((2-Amino-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)-5-bromo-2-chlorobenzamide (CAS 868974-98-5)
- 4-Bromo-5-[(4-chloro-2-methylphenoxy)methyl]-1-methyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one (CAS 1020252-11-2)
- 7784-23-8 L903Z8J9VR Aluminum iodide Aluminium iodide Aluminum iodide (AlI3) EINECS 232-054-8 UNII-L903Z8J9VR (CAS 7784-23-8)
- ethyl 2-[(2-chloroacetyl)amino]-3,3,3-trifluoro-2-hydroxypropanoate hydrate (CAS 328270-26-4)
- 3-(3-Chlorophenyl)-4-((4-ethoxy-3-methoxybenzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-26-4)
- 2-(6-(Tert-butyl)naphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1620789-31-2)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(quinolin-2-yl)propanoic acid (CAS 214852-58-1)
- 5-Amino-N-tert-butyl-2,4-difluorobenzene-1-sulfonamide (CAS 1036546-81-2)
- 2-(4-sec-Butylphenyl)-8-methylquinoline-4-carboxylic acid (CAS 932796-03-7)
- 2-Ethyl-2,3-dihydro-1-benzofuran-3-one (CAS 53614-65-6)
- Methyl 3-chloro-2-fluoro-5-(trifluoromethyl)benzoate (CAS 773874-03-6)
- 2-(4-Fluoro-3-methylphenyl)azetidine (CAS 777888-90-1)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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