N-(2-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)ethyl)-3-chloro-5-(trifluoromethyl)pyridin-2-amine CAS 477845-59-3

Purity 97%+In StockPharmaceutical Standards
CAS No.477845-59-3
Molecular FormulaC13H10ClF3N6
Molecular Weight342.71 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(2-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)ethyl)-3-chloro-5-(trifluoromethyl)pyridin-2-amine CAS 477845-59-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(2-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)ethyl)-3-chloro-5-(trifluoromethyl)pyridin-2-amine.

CATO supplies N-(2-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)ethyl)-3-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS 477845-59-3), a certified reference material (molecular formula C13H10ClF3N6, MW 342.71 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, N-(2-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)ethyl)-3-chloro-5-(trifluoromethyl)pyridin-2-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 342.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N-(2-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)ethyl)-3-chloro-5-(trifluoromethyl)pyridin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H10ClF3N6
Molecular Weight342.71 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms6

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