1-(5-((6-Chloroquinolin-2-yl)oxy)-2-nitrophenyl)ethanone CAS 90510-51-3
| CAS No. | 90510-51-3 |
| Molecular Formula | C17H11ClN2O4 |
| Molecular Weight | 342.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(5-((6-Chloroquinolin-2-yl)oxy)-2-nitrophenyl)ethanone (C17H11ClN2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
1-(5-((6-Chloroquinolin-2-yl)oxy)-2-nitrophenyl)ethanone (CAS 90510-51-3), molecular formula C17H11ClN2O4 and molecular weight 342.73 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H11ClN2O4 |
| Molecular Weight | 342.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloroquinolin Standards
- 1-{4-[(2-chloroquinolin-3-yl)methoxy]-3-methoxyphenyl}ethan-1-one (CAS 1803583-83-6)
- 3-(3-Benzyl-8-chloroquinolin-4-yl)phenol (CAS 854774-16-6)
- 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol (CAS 118-42-3)
- 3-((5-Chloroquinolin-8-yl)oxy)-5-(trifluoromethyl)picolinonitrile (CAS 338791-70-1)
- 8-((5-Chloroquinolin-8-yl)oxy)octyl acetate (CAS 88350-09-8)
- 4-Chloroquinolin-8-yl 4-methylbenzenesulfonate (CAS 1022094-18-3)
- 2-((5-Chloroquinolin-8-yl)oxy)-N-(2-propoxyacetoxy)acetimidamide (CAS 88758-63-8)
- 5-Chloroquinolin-8-yl (2-chlorophenyl)carbamate (CAS 20842-60-8)
Recommended Standards
- N-(2-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)ethyl)-3-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS 477845-59-3)
- 2-(2-Chlorophenoxy)-N'-(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)acetohydrazide (CAS 946386-04-5)
- Ethyl 2-(3-(2-chloro-6-fluorobenzyl)-2,4,5-trioxoimidazolidin-1-yl)acetate (CAS 303986-51-8)
- 5-(2-Chlorophenyl)-N-(2-nitrophenyl)furan-2-carboxamide (CAS 199458-85-0)
- 5-Methyl-2-(methylsulfonyl)aniline (CAS 876494-64-3)
- Tert-butyl (2R,3S)-3-amino-2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate (CAS 1277168-56-5)
- 2-[4-[2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-1-naphthalenyl]phenyl]-4,5-dihydro-4,4-dimethyloxazole (CAS 85678-98-4)
- 3-(4-Iodo-1h-pyrazol-1-yl)-2-(isopropylamino)-2-methylpropanoic acid (CAS 1340100-46-0)
- Methyl 3-nitro-4-(piperidin-1-yl)benzoate (CAS 32117-05-8)
- (3S,4R)-4-Methoxy-N-methylpyrrolidin-3-amine (CAS 771441-59-9)
- Fe(III) MeSoporphyrin IX chloride (CAS 21007-37-4)
- 2-cyclohexyl-6-methyl-3,4-dihydropyrimidin-4-one (CAS 94052-07-0)
- N-(4-Formylthiazol-2-yl)propionamide (CAS 904626-41-1)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
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