3-[(4-Fluorophenyl)methyl]-4-hydroxy-1-[(4-methoxyphenyl)methyl]-5-[(1E)-{[(4-methylphenyl)methoxy]imino}methyl]-1,2-dihydropyridin-2-one CAS 477846-01-8
| CAS No. | 477846-01-8 |
| Molecular Formula | C29H27FN2O4 |
| Molecular Weight | 486.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-[(4-Fluorophenyl)methyl]-4-hydroxy-1-[(4-methoxyphenyl)methyl]-5-[(1E)-{[(4-methylphenyl)methoxy]imino}methyl]-1,2-dihydropyridin-2-one (CAS 477846-01-8), molecular formula C29H27FN2O4 and molecular weight 486.53 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-[(4-Fluorophenyl)methyl]-4-hydroxy-1-[(4-methoxyphenyl)methyl]-5-[(1E)-{[(4-methylphenyl)methoxy]imino}methyl]-1,2-dihydropyridin-2-one (C29H27FN2O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-[(4-Fluorophenyl)methyl]-4-hydroxy-1-[(4-methoxyphenyl)methyl]-5-[(1E)-{[(4-methylphenyl)methoxy]imino}methyl]-1,2-dihydropyridin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H27FN2O4 |
| Molecular Weight | 486.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- 1-(7-(2-Fluorophenyl)-4-hydroxythieno[3,2-d]pyrimidin-2-yl)-N-(2-morpholinoethyl)piperidine-4-carboxamide (CAS 1242859-59-1)
- 1-Benzyl-3-[(4-fluorophenyl)methyl]-5-[(2E)-3-[(4-methoxyphenyl)amino]prop-2-enoyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 338399-43-2)
- 2-(5-((3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)ethanesulfonic acid (CAS 623933-09-5)
- [(4-Fluorophenyl)methyl][2-(2-{[1-(4-methylbenzenesulfonyl)-1H-indol-4-yl]oxy}ethoxy)ethyl]amine (CAS 477862-67-2)
- 1-(4-Fluorophenyl)-N-(1-((4-methoxyphenyl)sulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)methanesulfonamide (CAS 946346-88-9)
- 1-(4-Fluorophenyl)-4-(4-(2-((4-methoxyphenyl)(phenyl)methoxy)ethyl)piperazin-1-yl)butan-1-one (CAS 65329-79-5)
- 2-((2-(4-Fluorophenyl)-2-oxoethyl)thio)-3-(4-methoxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one (CAS 477329-18-3)
- 2-((2-((2-Fluorophenyl)sulfonamido)phenyl)thio)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 478045-38-4)
Recommended Standards
- 5-O-Trityl-3'-deoxy-3'-fluorothymidine (CAS 135197-63-6)
- 5-(4-Methylbenzenesulfonyl)-2-phenyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine (CAS 478247-28-8)
- Indobufen Impurity 63 (CAS CATO-C4X-179263)
- Olmesartan Impurity 116 (CAS 3092204-98-0)
- Methyl 2-(2-ethyl-7-oxo-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)acetate (CAS 908498-20-4)
- 4-Bromo-3-(difluoromethyl)-5-fluoropyridine-2-acetic acid (CAS 1806062-03-2)
- 1-(4-Hydroxyphenyl)-2-(isopropylthio)ethan-1-one (CAS 1178399-10-4)
- Isochromeno[3',4':4,5]pyrrolo[2,3-f]isoquinolin-8(13H)-one (CAS 5100-91-4)
- 5-Hydroxymethyl)-1H-indole-2-boronic acid (CAS 2377606-14-7)
- 4-(Azetidin-3-yl)phenol (CAS 4363-15-9)
- 1-(4-Fluorophenyl)-N-methyl-3-(methylthio)propan-2-amine (CAS 1247680-54-1)
- 2-Chloro-4-(cyclohexylmethoxy)pyridine (CAS 1341485-24-2)
- 1,2-Di([1,1'-biphenyl]-4-yl)ethyne (CAS 21326-80-7)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
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