5-(4-Methylbenzenesulfonyl)-2-phenyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine CAS 478247-28-8
| CAS No. | 478247-28-8 |
| Molecular Formula | C24H17F3N2O2S2 |
| Molecular Weight | 486.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 486.53 g/mol gives 5-(4-Methylbenzenesulfonyl)-2-phenyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(4-Methylbenzenesulfonyl)-2-phenyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine (CAS 478247-28-8) is a high-purity analytical reference standard with the molecular formula C24H17F3N2O2S2 and a molecular weight of 486.53 g/mol.
5-(4-Methylbenzenesulfonyl)-2-phenyl-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine (C24H17F3N2O2S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H17F3N2O2S2 |
| Molecular Weight | 486.53 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Methylbenzenesulfonyl Standards
- [2-(2-{[1-(4-methylbenzenesulfonyl)-1H-indol-4-yl]oxy}ethoxy)ethyl][2-(morpholin-4-yl)ethyl]amine (CAS 860785-84-8)
- 5-{[2-(2-{[1-(4-methylbenzenesulfonyl)-1H-indol-4-yl]oxy}ethoxy)ethyl]sulfanyl}-1,3,4-thiadiazol-2-amine (CAS 478040-20-9)
- [1-Methyl-5-(4-methylbenzenesulfonyl)-3-phenyl-1H-pyrazol-4-yl]methyl 3-chlorobenzoate (CAS 318247-62-0)
- (2Z)-2-(4-Methylbenzenesulfonyl)-3-[3-(naphthalen-2-yl)-1-phenyl-1H-pyrazol-4-yl]prop-2-enenitrile (CAS 957042-53-4)
- 3-[1-(4-methylbenzenesulfonyl)-3-(trifluoromethyl)-1h-pyrazol-4-yl]propyl 4-methylbenzene-1-sulfonate (CAS 1019069-06-7)
- 4,6-Bis(4-methylbenzenesulfonyl)-2-phenylpyrimidine (CAS 339105-57-6)
- 2-(4-Methylbenzenesulfonyl)-N-({[4-(trifluoromethoxy)phenyl]carbamothioyl}amino)acetamide (CAS 1022404-03-0)
- 4-Methyl-3-(3-methylbenzenesulfonyl)-1-[(4-methylphenyl)methyl]-6-phenyl-1,2-dihydropyridin-2-one (CAS 321431-52-1)
Recommended Standards
- 3-[(4-Fluorophenyl)methyl]-4-hydroxy-1-[(4-methoxyphenyl)methyl]-5-[(1E)-{[(4-methylphenyl)methoxy]imino}methyl]-1,2-dihydropyridin-2-one (CAS 477846-01-8)
- Olmesartan Impurity 116 (CAS 3092204-98-0)
- 5-O-Trityl-3'-deoxy-3'-fluorothymidine (CAS 135197-63-6)
- Fluticasone Impurity 50 (CAS CATO-C4X-165050)
- 4-(Difluoromethyl)-5-(trifluoromethyl)picolinic acid (CAS 1806815-14-4)
- N-(4-Chlorophenyl)-6-(Trifluoromethyl)-1,3,5-Triazine-2,4-Diamine (CAS 53387-70-5)
- 3-(1,3-Benzothiazol-2-yl)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-amine (CAS 1006596-05-9)
- 1-(Adamantan-1-yl)-4-methylpyridin-1-ium (CAS 773043-32-6)
- N-(2-(Dimethylamino)ethyl)-N-methyl-2-(methylamino)acetamide (CAS 1096804-88-4)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with (1-methylethenyl)benzene and 2-propenenitrile (CAS 25747-75-5)
- N'-benzoyl-2,6-bis(trifluoromethyl)isonicotinohydrazide (CAS 1092346-50-3)
- 2-Methoxy-N,N,N-trimethyl-2-oxoethan-1-aminium chloride (CAS 3032-10-8)
- 2-Bromo-6-(1H-imidazol-1-yl)pyridine (CAS 463336-62-1)
- Bradykinin-Like Neuropeptide (Aplysia californica) (H-1654.0001) (CAS 165174-60-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com