Methyl 5-(4-chlorobenzamido)benzo[b]thiophene-2-carboxylate CAS 477847-49-7
| CAS No. | 477847-49-7 |
| Molecular Formula | C17H12ClNO3S |
| Molecular Weight | 345.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 5-(4-chlorobenzamido)benzo[b]thiophene-2-carboxylate.
Methyl 5-(4-chlorobenzamido)benzo[b]thiophene-2-carboxylate (CAS 477847-49-7), molecular formula C17H12ClNO3S and molecular weight 345.80 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 5-(4-chlorobenzamido)benzo[b]thiophene-2-carboxylate (C17H12ClNO3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl 5-(4-chlorobenzamido)benzo[b]thiophene-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H12ClNO3S |
| Molecular Weight | 345.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- Methyl 5-(2-chlorobenzamido)benzo[b]thiophene-2-carboxylate (CAS 477847-55-5)
- Methyl 5-(3-chlorobenzamido)benzo[b]thiophene-2-carboxylate (CAS 477847-51-1)
- Ethyl 3-(2-chlorobenzamido)benzofuran-2-carboxylate (CAS 477498-96-7)
- (R)-2-(4-Chlorobenzamido)-3-(1H-indol-3-yl)propanoic acid (CAS 95672-29-0)
- 5-((4-Chlorobenzamido)methyl)thiophene-2-sulfonyl chloride (CAS 166964-34-7)
- N-(4-(4-chlorobenzamido)phenyl)nicotinamide (CAS 332376-88-2)
- 2-(4-Chlorobenzamido)-4,5,6,7-tetrahydrobenzo[d]thiazole-4-carboxylic acid (CAS 1019108-36-1)
- 2-(4-Chlorobenzamido)-N-(3-methylisoxazol-5-yl)benzamide (CAS 90059-33-9)
Recommended Standards
- N'-(2-chlorobenzoyl)-3-(1H-pyrrol-1-yl)thiophene-2-carbohydrazide (CAS 672925-35-8)
- N-(2-Chlorophenyl)-2-((4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetamide (CAS 678559-94-9)
- 5-(4-Chlorophenyl)-3-(phenylsulfonyl)pyridin-2(1H)-one (CAS 400089-33-0)
- N-(2-Chlorophenyl)-2-((6-(furan-2-yl)pyridazin-3-yl)thio)acetamide (CAS 922891-72-3)
- rel-(Methyl (3R,6S)-6-methylpiperidine-3-carboxylate) (CAS 1009376-78-6)
- N-(piperidin-4-ylmethyl)pentanamide (CAS 1016699-34-5)
- 2-Hydroxyethyl Methyl Terephthalate (CAS 3645-00-9)
- Methyl 5-(3,4-dimethoxyphenyl)-2-ethyl-7-methyl-3-oxo-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 617698-56-3)
- 8-Chloro-2-phenylquinazoline (CAS 58058-52-9)
- 1-(2-Cyclopropyl-5,6-dimethylpyrimidin-4-yl)piperidine-3-carboxylic acid (CAS 1707594-70-4)
- Ethyl 4-((2-ethoxy-3,4-dioxocyclobut-1-en-1-yl)amino)piperidine-1-carboxylate (CAS 933006-05-4)
- (S)-3-(4-Ethylphenyl)piperazin-2-one (CAS 1228568-42-0)
- (2,6-Difluoro-3-nitrophenyl)(phenyl)methanone (CAS 1145881-51-1)
- Semaglutide impurity 28 (CAS CATO-C4X-222628)
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