2,4-Bis(trifluoromethyl)-7-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,8-naphthyridine CAS 477851-80-2
| CAS No. | 477851-80-2 |
| Molecular Formula | C21H15F9N4 |
| Molecular Weight | 494.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2,4-Bis(trifluoromethyl)-7-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,8-naphthyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2,4-Bis(trifluoromethyl)-7-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,8-naphthyridine (CAS 477851-80-2), molecular formula C21H15F9N4 and molecular weight 494.36 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,4-Bis(trifluoromethyl)-7-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}-1,8-naphthyridine (C21H15F9N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H15F9N4 |
| Molecular Weight | 494.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Bis Standards
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Recommended Standards
- [1,1':4',1''-Terphenyl]-2',3,3'',5,5',5''-hexacarboxylic acid (CAS 1542274-12-3)
- Gossypetin 8-O-β-D-glucuronide (CAS 55366-56-8)
- 25-Iodo-2,5,8,11,14,17,20,23-octaoxapentacosane (CAS 1319730-07-8)
- Mal-NH-PEG2-CH2CH2COOPFP ester (CAS 1347750-81-5)
- 2-Amino-5-hydroxybenzonitrile (CAS 116423-58-6)
- N-(5,7-Dimethyl-3-(prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-ylidene)-1-(thiophen-2-ylsulfonyl)piperidine-4-carboxamide (CAS 941941-67-9)
- 1-Chloroheptane (CAS 629-06-1)
- (2E,4E)-2,5-Diphenylpenta-2,4-dienenitrile (CAS 6443-79-4)
- L-DOPA ethyl ester Hydrochloride (CAS 39740-30-2)
- 5-(4-Bromophenyl)-3-methylpentanoic acid (CAS 1343827-83-7)
- Lapatinib 2-Fluoro Impurity (CAS 1393112-45-2)
- 2-Chlorooxazolo[5,4-c]pyridine (CAS 916792-10-4)
- Tert-butyl (5R,6S)-6-methyl-2,8-diazaspiro[4.5]Decane-8-carboxylate (CAS 1899102-26-1)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com