7-(4-(Pyrimidin-2-yl)piperazin-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine CAS 477851-79-9
| CAS No. | 477851-79-9 |
| Molecular Formula | C18H14F6N6 |
| Molecular Weight | 428.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 7-(4-(Pyrimidin-2-yl)piperazin-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 477851-79-9), a certified reference material (molecular formula C18H14F6N6, MW 428.33 g/mol) for analytical method development and quality control.
7-(4-(Pyrimidin-2-yl)piperazin-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (C18H14F6N6) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H14F6N6 |
| Molecular Weight | 428.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Pyrimidin Standards
- Ethyl 3-((4-(pyrimidin-2-yl)piperazin-1-yl)sulfonyl)benzo[b]thiophene-2-carboxylate (CAS 941919-12-6)
- (S)-2-(1-((1-(pyrimidin-2-yl)-1H-imidazol-4-yl)methyl)piperidin-3-yl)-6-(thiophen-2-yl)pyrimidin-4(3H)-one (CAS 1825355-56-3)
- Phenyl pyrimidin-2-ylcarbamate (CAS 6324-09-0)
- (4-(Pyrimidin-2-yl)piperazin-1-yl)(2-(p-tolyl)quinolin-4-yl)methanone (CAS 546100-66-7)
- 1-(4-(4-(2-(Pyrimidin-2-ylamino)thiazole-4-carbonyl)piperazin-1-yl)phenyl)ethan-1-one (CAS 1251562-91-0)
- 2-(4-(4-(Pyrimidin-2-yl)piperazin-1-yl)butyl)benzo[d]isothiazol-3(2H)-one 1,1-dioxide (CAS 95847-70-4)
- 1-(2-((4-(Pyrimidin-2-yl)piperazin-1-yl)sulfonyl)ethyl)-3-(thiophen-2-yl)urea (CAS 1207005-68-2)
- 4-Oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-(tert-butyl)benzoate (CAS 877635-40-0)
Recommended Standards
- 2-(1,1-Dioxidothiomorpholino)-2-phenylethyl 3,4-dichlorobenzoate (CAS 338962-92-8)
- (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((3-methylbut-2-en-1-yl)amino)-2-(methylselanyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol (CAS 110085-70-6)
- 1,4-Bis(4-amino-2-trifluoromethylphenoxy)benzene (CAS 94525-05-0)
- (2E)-3-{4-[(4-bromophenyl)methoxy]phenyl}-N-[(thiophen-2-yl)methyl]prop-2-enamide (CAS 477889-37-5)
- 2-(2-Hydroxyadamantan-2-yl)acetonitrile (CAS 725246-77-5)
- (R)-2-Chloro-5-methoxy-6-(3-methylmorpholino)pyrimidine-4-carbaldehyde (CAS 2425604-21-1)
- N-(4-(Aminomethyl)-2-cyclopropoxyphenyl)methanesulfonamide (CAS 1243386-74-4)
- 1,3-Butadiene-1,1,4,4-d4 (gas) (stabilized with hydroquinone) (CAS 10545-58-1)
- 6-Bromo-2-ethylimidazo[1,2-a]pyridin-3-amine (CAS 1343280-51-2)
- 3-(3,4-Dimethoxyphenyl)-3-((4-methylphenyl)sulfonamido)propanoic acid (CAS 332052-67-2)
- 2-(4-Fluorophenyl)-N-hydroxyacetimidamide (CAS 925252-30-8)
- 2-Amino-2-methyl-3-(3-methyl-1h-pyrazol-1-yl)propanamide (CAS 1339869-34-9)
- 2-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)piperidine (CAS 1041561-95-8)
- Eosinophilotactic Peptide (CAS 61756-28-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com