5,7-Bis(trifluoromethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}-1,8-naphthyridin-2-amine CAS 477851-84-6
| CAS No. | 477851-84-6 |
| Molecular Formula | C18H10F9N3 |
| Molecular Weight | 439.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 5,7-Bis(trifluoromethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}-1,8-naphthyridin-2-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 439.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5,7-Bis(trifluoromethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}-1,8-naphthyridin-2-amine (CAS 477851-84-6) is a high-purity analytical reference standard with the molecular formula C18H10F9N3 and a molecular weight of 439.28 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5,7-Bis(trifluoromethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}-1,8-naphthyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H10F9N3 |
| Molecular Weight | 439.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Bis Standards
- 4-[3,5-Bis(trifluoromethyl)benzoyl]-8-methyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1326810-71-2)
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Recommended Standards
- 2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-4-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 478245-80-6)
- (S)-tert-Butyl 2-(5-(4-iodophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate (CAS 1242094-29-6)
- Ethyl 4-Bromo-7-oxo-1-tosyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate (CAS 1628864-25-4)
- (R)-tert-Butyl 2-(5-(4-iodophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate (CAS 1370600-39-7)
- 3,4-Dihydro-2H-spiro[isoquinoline-1,3'-oxetan]-6-amine (CAS 1823932-34-8)
- (R)-2-((1-((Benzyloxy)carbonyl)piperidin-3-yl)oxy)acetic acid (CAS 937057-83-5)
- bis(2,2,2-trifluoroethyl)amine hydrochloride (CAS 1193387-30-2)
- 1-(4-Chlorophenyl)-3-(3-(difluoromethoxy)phenyl)urea (CAS 886542-48-9)
- N-Boc-thiourea, 97% (CAS 268551-65-1)
- 2-(4-Bromo-2,6-dimethylphenoxy)ethan-1-amine (CAS 499980-87-9)
- 1-Chloro-3-ethylpent-2-ene (CAS 761-20-6)
- 4-Benzyl-5-(2-bromophenyl)-4h-1,2,4-triazole-3-thiol (CAS 718600-58-9)
- n-(1h-Pyrazol-4-yl)-2-(1,3,5-trimethyl-1h-pyrazol-4-yl)acetamide (CAS 1153801-78-5)
- Des-Gln19-Tirzepatide (CAS CATO-CPTD788954)
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