2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-4-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile CAS 478245-80-6
| CAS No. | 478245-80-6 |
| Molecular Formula | C20H11Cl2F3N2S |
| Molecular Weight | 439.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 439.28 g/mol gives 2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-4-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-4-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 478245-80-6), molecular formula C20H11Cl2F3N2S and molecular weight 439.28 g/mol, is a CATO reference standard with documented purity and traceability.
2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-4-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (C20H11Cl2F3N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H11Cl2F3N2S |
| Molecular Weight | 439.28 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related dichlorophenyl Standards
- [(3Z)-1-[(2,4-Dichlorophenyl)methyl]-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino 4-methylbenzoate (CAS 320419-61-2)
- 3-(2,4-Dichlorophenyl)-2,5-diphenyldihydro-2H-pyrrolo[3,4-d]isoxazole-4,6(5H,6aH)-dione (CAS 342615-08-1)
- 1-[(3,4-Dichlorophenyl)methyl]-3,4-bis(4-methoxyphenyl)-1H-pyrazole (CAS 956756-11-9)
- 1-{3-[7-(2,4-dichlorophenyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-2-yl}-2,5-dimethyl-1H-pyrrole (CAS 478258-96-7)
- 7-(2,4-Dichlorophenyl)-2-(3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)pyrazolo[1,5-a]pyrimidine (CAS 866049-49-2)
- N-(3,4-Dichlorophenyl)-2-(2,4-diphenyl-1,3-thiazol-5-yl)acetamide (CAS 339277-60-0)
- 2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-5-methoxy-4-[(4-methoxyphenyl)sulfanyl]pyrimidine (CAS 338955-53-6)
- 2-{[(3,4-dichlorophenyl)methyl]sulfanyl}-5-methoxy-4-[(4-methoxyphenyl)sulfanyl]pyrimidine (CAS 339275-99-9)
Recommended Standards
- Ethyl 4-Bromo-7-oxo-1-tosyl-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate (CAS 1628864-25-4)
- 5,7-Bis(trifluoromethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}-1,8-naphthyridin-2-amine (CAS 477851-84-6)
- Ligagliptin impurity 106 (CAS CATO-C4X-1101106)
- (S)-tert-Butyl 2-(5-(4-iodophenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate (CAS 1242094-29-6)
- 4-(Cbz-Amino)-2-fluorobenzeneboronic acid pinacol ester, 97% (CAS 1218791-13-9)
- 5-(2,2,3,3-Tetramethylcyclopropyl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1516015-63-6)
- 3-Vinylphenol(stabilized with TBC) (CAS 620-18-8)
- 6-bromo-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid (CAS 1094298-69-7)
- 4-Amino-5-methyl-1-(tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (CAS 18002-32-9)
- Varenicline Impurity 15 (CAS 2306217-11-6 (Free Base))
- (4-(3-Fluorophenoxy)pyridin-2-yl)methanamine (CAS 1250151-58-6)
- 2-Hydroxy-n-(2-phenoxyethyl)benzamide (CAS 13156-91-7)
- Diethyl 2-(2,4-dichloro-5-fluorobenzoyl)malonate (CAS 86483-50-3)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com