7-(4-Fluorophenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine CAS 477852-34-9

Purity 97%+In StockPharmaceutical Standards
CAS No.477852-34-9
Molecular FormulaC16H7F7N2O
Molecular Weight376.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-(4-Fluorophenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine CAS 477852-34-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-(4-Fluorophenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine.

7-(4-Fluorophenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 477852-34-9) is a high-purity analytical reference standard with the molecular formula C16H7F7N2O and a molecular weight of 376.23 g/mol.

7-(4-Fluorophenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (C16H7F7N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 7-(4-Fluorophenoxy)-2,4-bis(trifluoromethyl)-1,8-naphthyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H7F7N2O
Molecular Weight376.23 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

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