2,4-Bis(trifluoromethyl)-7-[4-(trifluoromethyl)phenoxy]-1,8-naphthyridine CAS 477852-35-0
| CAS No. | 477852-35-0 |
| Molecular Formula | C17H7F9N2O |
| Molecular Weight | 426.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2,4-Bis(trifluoromethyl)-7-[4-(trifluoromethyl)phenoxy]-1,8-naphthyridine (CAS 477852-35-0), a certified reference material (molecular formula C17H7F9N2O, MW 426.24 g/mol) for analytical method development and quality control.
Based on its molecular formula C17H7F9N2O, 2,4-Bis(trifluoromethyl)-7-[4-(trifluoromethyl)phenoxy]-1,8-naphthyridine contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 426.24 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H7F9N2O |
| Molecular Weight | 426.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Bis Standards
- 2,4-Bis(trifluoromethyl)-7-[3-(trifluoromethyl)phenoxy]-1,8-naphthyridine (CAS 303996-18-1)
- 3-{5-[3,5-di(trifluoromethyl)phenyl]-2-furyl}-1-(2-hydroxyphenyl)prop-2-en-1-one (CAS 680579-63-9)
- 16,18-Bis(trifluoromethyl)-3,13,19-triazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4(9),5,7,15(20),16,18-heptaen-14-one (CAS 860785-41-7)
- 5,7-bis(trifluoromethyl)-N-[3-(trifluoromethyl)phenyl][1,8]naphthyridin-2-amine (CAS 241488-36-8)
- 3-(Trifluoromethyl)phenyl 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylate (CAS 1795491-19-8)
- 3-[3,5-Bis(trifluoromethyl)pyridin-2-yl]-1-(4-methylbenzenesulfonyl)urea (CAS 866043-24-5)
- 4-(Trifluoromethyl)-5-(tributylstannyl)pyrazole (CAS 790661-62-0)
- 1-(3,5-Bis(trifluoromethyl)benzyl)-3-((1S,2S)-2-(dimethylamino)cyclohexyl)thiourea (CAS 1908529-26-9)
Recommended Standards
- 4-Chloro-N-(3-chloro-4-(cyano(phenyl)methyl)phenyl)-3-nitrobenzamide (CAS 1386651-12-2)
- 2,3-Dichloro-4-(ethylsulfonyl)-N-(4-(trifluoromethyl)phenyl)benzamide (CAS 477867-71-3)
- Methyl 3-ethoxy-5-iodo-4-((4-methylbenzyl)oxy)benzoate (CAS 1706448-08-9)
- (E)-5-((2-chlorobenzyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde O-(2-chloroacetyl) oxime (CAS 321553-34-8)
- 4-(4-Fluorophenyl)-6-isopropylpyrimidin-2-ol (CAS 894787-95-2)
- 1-[2-(5-Chloro-1H-indol-3-yl)ethyl]-5-oxopyrrolidine-3-carboxylic acid (CAS 931374-75-3)
- 4-Chloro-3-(difluoromethyl)-5-methoxypyridine (CAS 1806782-90-0)
- 2-cyano-N-[(hydroxyimino)methyl]-3-phenylacrylamide (CAS 303994-83-4)
- Tranilast Impurity 11 (CAS CATO-C4X-252911)
- (1-Tert-butylazetidin-2-yl)methanamine (CAS 31309-40-7)
- (3,4-Difluorophenyl)(4-((2-ethyl-1H-imidazol-1-yl)methyl)piperidin-1-yl)methanone (CAS 1351595-58-8)
- 3-Isobutyl-5-(piperidin-2-yl)-1,2,4-oxadiazole hydrochloride (CAS 1380300-31-1)
- 3,5-Dimethyl-4-(1H-pyrrolo[3,2-b]pyridin-6-yl)isoxazole (CAS 1627925-75-0)
- (D-Trp32)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 153549-78-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com