4-((4-Chlorophenyl)thio)-2-phenylpyrimidine-5-carboxylic acid CAS 477854-49-2

Purity 97%+In StockPharmaceutical Standards
CAS No.477854-49-2
Molecular FormulaC17H11ClN2O2S
Molecular Weight342.80 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-((4-Chlorophenyl)thio)-2-phenylpyrimidine-5-carboxylic acid CAS 477854-49-2 chemical structure

Description

4-((4-Chlorophenyl)thio)-2-phenylpyrimidine-5-carboxylic acid (C17H11ClN2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

4-((4-Chlorophenyl)thio)-2-phenylpyrimidine-5-carboxylic acid (CAS 477854-49-2), molecular formula C17H11ClN2O2S and molecular weight 342.80 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-((4-Chlorophenyl)thio)-2-phenylpyrimidine-5-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC17H11ClN2O2S
Molecular Weight342.80 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

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