4-(3-Chlorobenzo[b]thiophene-2-carbonyl)-3,4-dihydroquinoxalin-2(1H)-one CAS 728027-13-2
| CAS No. | 728027-13-2 |
| Molecular Formula | C17H11ClN2O2S |
| Molecular Weight | 342.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(3-Chlorobenzo[b]thiophene-2-carbonyl)-3,4-dihydroquinoxalin-2(1H)-one is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-(3-Chlorobenzo[b]thiophene-2-carbonyl)-3,4-dihydroquinoxalin-2(1H)-one (CAS 728027-13-2), a certified reference material (molecular formula C17H11ClN2O2S, MW 342.80 g/mol) for analytical method development and quality control.
The molecular framework of 4-(3-Chlorobenzo[b]thiophene-2-carbonyl)-3,4-dihydroquinoxalin-2(1H)-one (C17H11ClN2O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(3-Chlorobenzo[b]thiophene-2-carbonyl)-3,4-dihydroquinoxalin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H11ClN2O2S |
| Molecular Weight | 342.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorobenzo Standards
- 4-(3-((5-Chlorobenzo[b]thiophen-7-yl)amino)-1H-pyrazol-5-yl)phenol (CAS 1301750-00-4)
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- 5-(3-Chlorobenzo[b]thiophen-2-yl)-4-phenyl-4h-1,2,4-triazole-3-thiol (CAS 140181-77-7)
- Methyl 2-((5-(3-chlorobenzo[b]thiophen-2-yl)-1,3,4-oxadiazol-2-yl)thio)acetate (CAS 433694-47-4)
- 2-((4-Chlorobenzo[d]thiazol-2-yl)(methyl)amino)-N-((tetrahydrofuran-2-yl)methyl)acetamide (CAS 1396783-03-1)
- 2-((4-Chlorobenzo[d]thiazol-2-yl)(methyl)amino)-N-(pyridin-2-ylmethyl)acetamide (CAS 1396635-32-7)
- 3-(5-Chlorobenzo[d]oxazol-2-yl)-7-hydroxy-2-oxo-2H-chromene-4-carbonitrile (CAS 97477-81-1)
- 2-((5-Chlorobenzo[d]oxazol-2-yl)thio)-1-(4-chlorophenyl)ethan-1-one (CAS 338417-18-8)
Recommended Standards
- 4-((4-Chlorophenyl)thio)-2-phenylpyrimidine-5-carboxylic acid (CAS 477854-49-2)
- 4-[(3-Chlorophenyl)sulfanyl]-2-phenylpyrimidine-5-carboxylic acid (CAS 477854-55-0)
- 4-((2-Chlorophenyl)thio)-2-phenylpyrimidine-5-carboxylic acid (CAS 400076-29-1)
- 4-Chloro-2-cyclohexyl-1,3-dioxoisoindoline-5-sulfonamide (CAS 40739-56-8)
- 3-((4-Chlorobenzyl)sulfinyl)-4-ethyl-5-((3-(trifluoromethyl)phenoxy)methyl)-4H-1,2,4-triazole (CAS 956607-36-6)
- Methyl (R)-3-amino-3-(3,5-dibromophenyl)propanoate (CAS 1213961-64-8)
- 2-Sulfanyl-5H,6H,7H-cyclopenta[b]pyridine-3-carboxylic acid (CAS 933728-88-2)
- (E)-6-(2-((4-iodophenyl)amino)vinyl)pyrazolo[1,5-a]pyrido[3,4-e]pyrimidine-3-carbonitrile (CAS 338966-86-2)
- 3-Chloro-6-(pyrrolidine-1-carbonyl)pyridazine (CAS 1182931-73-2)
- 5-(Piperazin-1-ylmethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 1242281-57-7)
- 4-Chloro-6-methylpicolinic acid hydrochloride (CAS 1841081-42-2)
- tert-Butyl 1,5-diazaspiro[3.4]octane-5-carboxylate (CAS 1334499-66-9)
- 4-(Acridin-9-yl)-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one (CAS 90878-34-5)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
Why CATO?
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