Methyl 2-{1-[(4-fluorophenyl)methyl]-4-hydroxy-2-oxo-1,2-dihydropyridin-3-yl}acetate CAS 477858-74-5
| CAS No. | 477858-74-5 |
| Molecular Formula | C15H14FNO4 |
| Molecular Weight | 291.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Methyl 2-{1-[(4-fluorophenyl)methyl]-4-hydroxy-2-oxo-1,2-dihydropyridin-3-yl}acetate (CAS 477858-74-5), a certified reference material (molecular formula C15H14FNO4, MW 291.27 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 2-{1-[(4-fluorophenyl)methyl]-4-hydroxy-2-oxo-1,2-dihydropyridin-3-yl}acetate (C15H14FNO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H14FNO4 |
| Molecular Weight | 291.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- (S)-Methyl 3-amino-3-(4-bromophenyl)propanoate hydrochloride (CAS 1245606-63-6)
- N-Me-D-Glu-OH (F-4240.0001) (CAS 77481-28-8)
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- 4-Bromo-1-(tert-butyldimethylsilyl)indole (CAS 193694-04-1)
- 4-(5-(4-Methylbenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid (CAS 300826-70-4)
- Dotinurad Impurity 5 (CAS 1285572-89-5)
- Peptide Impurity 13 (CAS CATO-CPTD788813)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com