6,7-Dimethoxy-N-{[3-(trifluoromethyl)phenyl]methyl}quinazolin-4-amine CAS 477859-89-5
| CAS No. | 477859-89-5 |
| Molecular Formula | C18H16F3N3O2 |
| Molecular Weight | 363.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6,7-Dimethoxy-N-{[3-(trifluoromethyl)phenyl]methyl}quinazolin-4-amine (CAS 477859-89-5) is a high-purity analytical reference standard with the molecular formula C18H16F3N3O2 and a molecular weight of 363.33 g/mol.
Structurally, 6,7-Dimethoxy-N-{[3-(trifluoromethyl)phenyl]methyl}quinazolin-4-amine (C18H16F3N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 363.33 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 6,7-Dimethoxy-N-{[3-(trifluoromethyl)phenyl]methyl}quinazolin-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16F3N3O2 |
| Molecular Weight | 363.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Dimethoxy Standards
- 6,7-Dimethoxy-N-(2-(trifluoromethyl)benzyl)quinazolin-4-amine (CAS 477855-26-8)
- 4,6-Dimethoxy-N-(4-(trifluoromethyl)phenyl)pyrimidine-5-sulfonamide (CAS 861208-73-3)
- 1,2-Dimethoxy-12-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridin-13(12H)-one (CAS 28342-33-8)
- 6,7-Dimethoxy-1-(4-(trifluoromethyl)phenethyl)-3,4-dihydroisoquinoline (CAS 324076-69-9)
- 2,5-Dimethoxy-N-[3-(phenethyloxy)benzyl]aniline (CAS 1040688-63-8)
- 2-Benzyl-6,7-dimethoxy-3-methyl-5-propyl-1-naphthaldehyde (CAS 1956380-09-8)
- 6,8-Dimethoxy-4-methyl-1-[4-(propan-2-yl)phenyl]-1H,2H,3H-pyrrolo[3,2-c]quinoline (CAS 860789-38-4)
- 6,7-Dimethoxy-8-((6-methoxyisoquinolin-7-yl)oxy)isoquinoline (CAS 87179-86-0)
Recommended Standards
- 6-Methoxy-N-(3-(trifluoromethyl)benzyl)-2H-chromene-3-carboxamide (CAS 338760-52-4)
- 5-Methyl-2-(2-phenoxyethyl)-4-(3-(trifluoromethyl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 861206-75-9)
- 8-Methoxy-N-(3-(trifluoromethyl)benzyl)-2H-chromene-3-carboxamide (CAS 338419-99-1)
- 4-(4-Methoxyphenyl)-5-methyl-2-(3-(trifluoromethyl)benzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 861206-14-6)
- 4-(Trifluoromethyl)furan-2(5H)-one (CAS 102854-63-7)
- N-(3-Isopropoxypropyl)-2-(5-methyl-7-oxo-3-phenyl-7H-furo[3,2-g]chromen-6-yl)acetamide (CAS 865282-93-5)
- 4-(1,3-Dioxoisoindolin-2-yl)-N-((hydroxymethyl)carbamoyl)benzenesulfonamide (CAS 16508-61-5)
- 5-Chloro-2-((4-methylbenzyl)oxy)benzaldehyde (CAS 590360-23-9)
- (Z)-3-((2-chloroacetoxy)imino)-1-(4-methylbenzyl)indolin-2-one (CAS 303149-28-2)
- Tert-butyl (2S,5R)-2-(bromomethyl)-5-methylmorpholine-4-carboxylate (CAS 2440199-06-2)
- 9,10-Anthracenedione, 1-amino-4-hydroxy-2-[(6-hydroxyhexyl)oxy]- (CAS 34231-26-0)
- 1,3,6-Tribromopyrene (CAS 38303-36-5)
- Isopropyl 2-amino-4-(4-propylphenyl)thiophene-3-carboxylate (CAS 351157-82-9)
- Tau Peptide (337-368) (Repeat 4 Domain) trifluoroacetate salt (CAS 330456-27-4)
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