4'-Chloro-2,3-difluoro-1,1'-biphenyl CAS 477860-10-9
| CAS No. | 477860-10-9 |
| Molecular Formula | C12H7ClF2 |
| Molecular Weight | 224.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4'-Chloro-2,3-difluoro-1,1'-biphenyl is closely related to fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4'-Chloro-2,3-difluoro-1,1'-biphenyl (CAS 477860-10-9) is a high-purity analytical reference standard with the molecular formula C12H7ClF2 and a molecular weight of 224.63 g/mol.
The molecular framework of 4'-Chloro-2,3-difluoro-1,1'-biphenyl (C12H7ClF2) is characterized by fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4'-Chloro-2,3-difluoro-1,1'-biphenyl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7ClF2 |
| Molecular Weight | 224.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
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