3-(((2-Chlorophenyl)thio)methyl)-2,3-dihydro-5H-thiazolo[2,3-b]quinazolin-5-one CAS 477860-19-8
| CAS No. | 477860-19-8 |
| Molecular Formula | C17H13ClN2OS2 |
| Molecular Weight | 360.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(((2-Chlorophenyl)thio)methyl)-2,3-dihydro-5H-thiazolo[2,3-b]quinazolin-5-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 3-(((2-Chlorophenyl)thio)methyl)-2,3-dihydro-5H-thiazolo[2,3-b]quinazolin-5-one (CAS 477860-19-8), a certified reference material (molecular formula C17H13ClN2OS2, MW 360.88 g/mol) for analytical method development and quality control.
The molecular framework of 3-(((2-Chlorophenyl)thio)methyl)-2,3-dihydro-5H-thiazolo[2,3-b]quinazolin-5-one (C17H13ClN2OS2) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H13ClN2OS2 |
| Molecular Weight | 360.88 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 1-(4-Chlorophenyl)-3-((3-fluoropropyl)thio)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (CAS 691868-87-8)
- 2-((3-Chlorophenyl)thio)-N-(4-phenylthiazol-2-yl)acetamide (CAS 338957-86-1)
- 2-(4-Chlorophenyl)-4-(4-ethyl-5-(prop-2-yn-1-ylthio)-4H-1,2,4-triazol-3-yl)thiazole (CAS 400083-62-7)
- 2-[(4-Chlorophenyl)sulfanyl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide (CAS 338957-72-5)
- 3-(((3-Chlorophenyl)thio)methyl)-2,3-dihydro-5H-thiazolo[2,3-b]quinazolin-5-one (CAS 477860-20-1)
- 3-(((4-Chlorophenyl)thio)methyl)-2,3-dihydro-5H-thiazolo[2,3-b]quinazolin-5-one (CAS 477855-78-0)
- N-(4-(4-chlorophenyl)thiazol-2-yl)-2-(phenylthio)acetamide (CAS 338959-60-7)
- 3-(2-Chlorophenyl)-1-(furan-2-ylmethyl)-1-(2-(thiophen-2-yl)ethyl)urea (CAS 1396853-47-6)
Recommended Standards
- 2,3,3',4,5',6-Hexachlorobiphenyl (CAS 74472-43-8)
- 4-Chloro-5-((4-cyclohexylbenzyl)oxy)-2-propylpyridazin-3(2H)-one (CAS 88094-46-6)
- 4-Chloro-5-(1-(4-cyclohexylphenyl)ethoxy)-2-ethylpyridazin-3(2H)-one (CAS 88093-58-7)
- 1-Benzhydryl-6'-chlorospiro[azetidine-3,3'-indoline] (CAS 2199794-32-4)
- Methyl 4-Fluoro-β-methyl-benzenepropanoate (CAS 24254-64-6)
- 3-Phosphoglyceric Acid (CAS 820-11-1)
- 2-(Chloromethyl)-4-(naphthalen-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 1206970-47-9)
- 3-[(2-Furylmethyl)amino]-5,5-dimethylcyclohex-2-en-1-one (CAS 325853-48-3)
- 3-(3-Fluorophenoxy)-1-propanol (CAS 133077-41-5)
- Poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-hydroxy-, polymer with 1,6-diisocyanatohexane (CAS 9048-90-2)
- 7-Bromo-3,4-dihydrobenzo[b]thiepin-5(2H)-one (CAS 15084-55-6)
- N-(4-(Methylsulfonyl)phenyl)thiophene-2-sulfonamide (CAS 900135-66-2)
- 2-(2-(Thiophen-2-yl)thiazol-5-yl)ethanamine (CAS 1206980-41-7)
- Semaglutide Impurity 9 (CAS CATO-C4X-22269)
Why CATO?
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