3-{[(4-bromophenyl)sulfanyl]methyl}-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-5-one CAS 477860-18-7
| CAS No. | 477860-18-7 |
| Molecular Formula | C17H13BrN2OS2 |
| Molecular Weight | 405.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-{[(4-bromophenyl)sulfanyl]methyl}-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-5-one (CAS 477860-18-7) is a high-purity analytical reference standard with the molecular formula C17H13BrN2OS2 and a molecular weight of 405.33 g/mol.
The molecular framework of 3-{[(4-bromophenyl)sulfanyl]methyl}-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-5-one (C17H13BrN2OS2) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-{[(4-bromophenyl)sulfanyl]methyl}-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-5-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H13BrN2OS2 |
| Molecular Weight | 405.33 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related bromophenyl Standards
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Recommended Standards
- 2-Amino-6-{4-[3-(trifluoromethyl)phenoxy]phenyl}pyridine-3,4,5-tricarbonitrile (CAS 478248-02-1)
- N-(2-Methoxyphenyl)-4-oxo-1-[4-(trifluoromethoxy)phenyl]-1,4-dihydropyridazine-3-carboxamide (CAS 478063-31-9)
- 1-Benzyl-2,6-dioxo-N-(4-(trifluoromethoxy)phenyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 338412-65-0)
- 2-bromo-1-(5-(tert-butyl)-[1,1'-biphenyl]-2-yl)-1H-benzo[d]imidazole (CAS CATO-CIM-105076)
- 5-(2,5-Dimethoxy-phenyl)-2H-pyrazole-3-carboxylic acid 890621-06-4 RTR-028002 (CAS 890621-06-4)
- n-(3-Ethoxypropyl)-4-methylcyclohexan-1-amine (CAS 416868-93-4)
- 3-Ethyl-4-methoxybenzoic acid methyl ester (CAS 102820-38-2)
- Tert-butyl (3aR,7aS)-octahydro-5H-pyrrolo[3,4-c]pyridine-5-carboxylate (CAS 1932642-17-5)
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- Ethyl 3-(2-bromophenyl)-3-cyanopropanoate (CAS 1864058-19-4)
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- 2-(2-Chlorophenyl)benzo[d]oxazol-5-amine (CAS 293737-79-8)
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