4-Bromo-2-[(2Z)-2-(4-chlorophenyl)-2-(methoxyimino)ethyl]-5-(diethylamino)-2,3-dihydropyridazin-3-one CAS 477860-48-3
| CAS No. | 477860-48-3 |
| Molecular Formula | C17H20BrClN4O2 |
| Molecular Weight | 427.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Bromo-2-[(2Z)-2-(4-chlorophenyl)-2-(methoxyimino)ethyl]-5-(diethylamino)-2,3-dihydropyridazin-3-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Bromo-2-[(2Z)-2-(4-chlorophenyl)-2-(methoxyimino)ethyl]-5-(diethylamino)-2,3-dihydropyridazin-3-one (CAS 477860-48-3), molecular formula C17H20BrClN4O2 and molecular weight 427.72 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Bromo-2-[(2Z)-2-(4-chlorophenyl)-2-(methoxyimino)ethyl]-5-(diethylamino)-2,3-dihydropyridazin-3-one (C17H20BrClN4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H20BrClN4O2 |
| Molecular Weight | 427.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 4 |
Related Bromo Standards
- 2-Bromo-N-(5-chloro-3-(phenylsulfonyl)-1H-indol-2-yl)acetamide (CAS 918494-37-8)
- 8-Bromo-7-(4-bromobenzyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (CAS 255730-99-5)
- Bromo(hexyl)triphenyl-l5-phosphane (CAS 39521-32-9)
- 4-Bromo-5-((2,4-dichlorophenoxy)methyl)-1-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 1024052-48-9)
- 6-Bromo-N,N-bis(4-methoxybenzyl)-4-methylpyridin-2-amine (CAS 1615656-13-7)
- 1,5-Bis(2-bromo-5-hydroxyphenyl)pentan-3-one (CAS 1427054-10-1)
- 3-Bromo-5-methyl-2-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 956370-57-3)
- Benzyl 2-(5-bromo-1H-indole-3-carbonyl)pyrrolidine-1-carboxylate (CAS 331842-86-5)
Recommended Standards
- tert-Butyl 4-(7-bromo-6-chloroquinazolin-4-yl)piperazine-1-carboxylate (CAS 1698027-00-7)
- 2-{[(4-chlorophenyl)methyl]sulfanyl}-4-(3,5-dichlorophenoxy)-5-methoxypyrimidine (CAS 338423-19-1)
- N-(4-Chlorophenyl)-2-(3,4-dichlorophenyl)quinoline-4-carboxamide (CAS 332175-87-8)
- 4-(4-Chlorophenoxy)-2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-5-methoxypyrimidine (CAS 339275-89-7)
- 7-Benzyl-4-chloro-2-(methylthio)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-8,8-d2 (CAS 2641914-94-3)
- (2-(Dimethylamino)pyridin-4-yl)methanol hydrochloride (CAS 1269189-05-0)
- Rhodojaponin-III (CAS 26342-66-5)
- Methyl 3-(2-methylpiperazin-1-yl)propanoate dihydrochloride (CAS 1432679-92-9)
- 4-Methyl-N-((1S,2S)-2-((2-methyl-6-propoxyphenyl)thio)-2,3-dihydro-1H-inden-1-yl)benzenesulfonamide (CAS 2411719-33-8)
- N-Nitroso Ramipril (CAS CATO-C4X-174422)
- (1-methylcyclopropyl)hydrazine;hydrochloride (CAS 2737246-42-1)
- Methyl 2-(1-methyl-1H-pyrazol-4-yl)tetrahydro-2H-pyran-4-carboxylate (CAS 2432830-24-3)
- Fmoc-5-amino-2,4-dimethoxy-benzoic acid (CAS 1076196-98-9)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com