3-Bromo-5-methyl-2-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine CAS 956370-57-3
| CAS No. | 956370-57-3 |
| Molecular Formula | C13H8BrF6N5 |
| Molecular Weight | 428.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Bromo-5-methyl-2-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Bromo-5-methyl-2-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 956370-57-3), molecular formula C13H8BrF6N5 and molecular weight 428.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Bromo-5-methyl-2-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (C13H8BrF6N5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Bromo-5-methyl-2-(1-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H8BrF6N5 |
| Molecular Weight | 428.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
- Bromopropylate (CAS 18181-80-1)
- 5-((4-Bromophenyl)thio)-4-chloro-2-(3-chlorophenyl)pyridazin-3(2H)-one (CAS 320421-80-5)
- Elagolix Impurity 3 (CAS 1150560-54-5)
- 5-(4-Bromobenzoyl)-N-(3,4-dichlorophenyl)-1,3-thiazol-2-amine (CAS 339023-03-9)
- 5-(2-Nitroethyl)-benzo[1,3]dioxole (CAS 21473-47-2)
- 3-(Cyclohex-1-en-1-yl)-1H-indole-6-carboxylic acid (CAS 494799-16-5)
- 1-Ethyl-5-methyl-1H-pyrazole-3-carboxamide (CAS 863752-20-9)
- 2-(Furan-2-yl)-2-(methylamino)acetonitrile hydrochloride (CAS 24026-94-6)
- 1-(2-Ethylphenyl)-4-(1-methyl-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one (CAS 876723-96-5)
- Relebactam Impurity 123 (CAS CATO-C4X-2144123)
- 4-Ethyl-3-(5-ethylthiophen-2-yl)-1h-pyrazol-5-amine (CAS 1329120-26-4)
- 5,5'-((4-Bromophenyl)methylene)bis(2-methylfuran) (CAS 86698-37-5)
- N-(3-Chlorophenyl)-1,1-dioxo-2,3-dihydrothiophen-3-amine (CAS 321977-85-9)
- Des-Pro-Pro-Tirzepatide (CAS CATO-CPTD788696)
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