6-Phenyl-5-(4-(3-(trifluoromethyl)benzoyl)piperazin-1-yl)pyridazin-3(2H)-one CAS 477863-62-0

Purity 97%+In StockPharmaceutical Standards
CAS No.477863-62-0
Molecular FormulaC22H19F3N4O2
Molecular Weight428.41 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Phenyl-5-(4-(3-(trifluoromethyl)benzoyl)piperazin-1-yl)pyridazin-3(2H)-one CAS 477863-62-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 428.41 g/mol gives 6-Phenyl-5-(4-(3-(trifluoromethyl)benzoyl)piperazin-1-yl)pyridazin-3(2H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

6-Phenyl-5-(4-(3-(trifluoromethyl)benzoyl)piperazin-1-yl)pyridazin-3(2H)-one (CAS 477863-62-0) is a high-purity analytical reference standard with the molecular formula C22H19F3N4O2 and a molecular weight of 428.41 g/mol.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 6-Phenyl-5-(4-(3-(trifluoromethyl)benzoyl)piperazin-1-yl)pyridazin-3(2H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 428.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC22H19F3N4O2
Molecular Weight428.41 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms4

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