4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-1-(3-methoxypropyl)-5-(4-nitrophenyl)-1H-pyrrol-2(5H)-one CAS 618074-12-7
| CAS No. | 618074-12-7 |
| Molecular Formula | C22H21FN2O6 |
| Molecular Weight | 428.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-1-(3-methoxypropyl)-5-(4-nitrophenyl)-1H-pyrrol-2(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-1-(3-methoxypropyl)-5-(4-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 618074-12-7) is a high-purity analytical reference standard with the molecular formula C22H21FN2O6 and a molecular weight of 428.41 g/mol.
4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-1-(3-methoxypropyl)-5-(4-nitrophenyl)-1H-pyrrol-2(5H)-one (C22H21FN2O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C22H21FN2O6 |
| Molecular Weight | 428.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 3-[1-(3-Fluoro-4-methoxybenzoyl)piperidin-4-yl]-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775506-76-7)
- 3-Fluoro-4-((6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-yl)oxy)aniline (CAS 1426956-97-9)
- 5-Fluoro-1-(2-((4-fluoro-2-methoxy-5-nitrophenyl)amino)pyrimidin-4-yl)-3-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 2050908-32-0)
- 3-[2-[4-[(4-Fluoro-2-hydroxyphenyl)(hydroxyimino)methyl]-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; (CAS 1391062-47-7)
- 3-Fluoro-4-((6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yl)oxy)aniline (CAS 479690-10-3)
- N-(3-Fluoro-4-methylphenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775354-41-0)
- 1-[4-[3-[4-(4-Fluoro-2-hydroxybenzoyl)-1-piperidinyl]propoxy]-3-methoxyphenyl]-ethanone (CAS 170170-50-0)
- 5-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1241950-72-0)
Recommended Standards
- 3,5-Diiodobenzene-1-sulfonyl chloride (CAS 57598-13-7)
- 4,4'-((5,6-Difluorobenzo[c][1,2,5]thiadiazole-4,7-diyl)bis(ethyne-2,1-diyl))dibenzaldehyde (CAS 2460375-95-3)
- Melarsomine (CAS 128470-15-5)
- 6-Phenyl-5-(4-(3-(trifluoromethyl)benzoyl)piperazin-1-yl)pyridazin-3(2H)-one (CAS 477863-62-0)
- 5-Bromo-6-methylindole-3-acetic Acid (CAS 1388058-00-1)
- 1-(Pyridin-4-yl)piperidin-4-ol (CAS 130658-65-0)
- N-(3-isopropoxypropyl)furan-3-carboxamide (CAS 1210319-14-4)
- Dotinurad Impurity 163 (CAS CATO-C4X-2494163)
- N-((6-(1H-Imidazol-1-yl)pyridin-3-yl)methyl)-5-(pyrrolidin-1-ylsulfonyl)pyridin-2-amine (CAS 1011092-55-9)
- Lufenuron EP Impurity E (CAS 103015-79-8)
- Tert-butyl 4-(4-(5-cyclohexyl-1,2,4-oxadiazol-3-yl)phenyl)piperazine-1-carboxylate (CAS 1272756-48-5)
- 4-(3-(Trifluoromethyl)phenyl)azetidin-2-one (CAS 777885-68-4)
- 8-Bromoquinoxaline-6-carbonitrile (CAS 1378254-84-2)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com