2-Chloro-N'-(2,5-dichlorophenyl)pyridine-3-carbohydrazide CAS 477864-50-9

Purity 97%+In StockPharmaceutical Standards
CAS No.477864-50-9
Molecular FormulaC12H8Cl3N3O
Molecular Weight316.57 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-N'-(2,5-dichlorophenyl)pyridine-3-carbohydrazide CAS 477864-50-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-N'-(2,5-dichlorophenyl)pyridine-3-carbohydrazide.

2-Chloro-N'-(2,5-dichlorophenyl)pyridine-3-carbohydrazide (CAS 477864-50-9), molecular formula C12H8Cl3N3O and molecular weight 316.57 g/mol, is a CATO reference standard with documented purity and traceability.

2-Chloro-N'-(2,5-dichlorophenyl)pyridine-3-carbohydrazide (C12H8Cl3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Chloro-N'-(2,5-dichlorophenyl)pyridine-3-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H8Cl3N3O
Molecular Weight316.57 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms3

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