[(3Z)-5-Chloro-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino acetate CAS 477864-51-0
| CAS No. | 477864-51-0 |
| Molecular Formula | C18H12ClF3N2O3 |
| Molecular Weight | 396.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of [(3Z)-5-Chloro-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino acetate (C18H12ClF3N2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
[(3Z)-5-Chloro-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino acetate (CAS 477864-51-0), molecular formula C18H12ClF3N2O3 and molecular weight 396.75 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures [(3Z)-5-Chloro-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-2,3-dihydro-1H-indol-3-ylidene]amino acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12ClF3N2O3 |
| Molecular Weight | 396.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Z Standards
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Recommended Standards
- (Z)-3-((2-chloroacetoxy)imino)-1-(3-(trifluoromethyl)benzyl)indolin-2-one (CAS 303996-88-5)
- [1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl]methyl N-[3-(trifluoromethyl)phenyl]carbamate (CAS 338419-13-9)
- 1-(4-Chlorobenzyl)-3-(3-(trifluoromethyl)benzyl)imidazolidine-2,4,5-trione (CAS 478262-69-0)
- Eldecalcitol Impurity 58 (CAS CATO-C4X-214058)
- 2-Ethoxy-4-(3-hydroxybutyl)phenol (CAS 1283091-06-4)
- 3-((2-Chloropyrimidin-4-yl)amino)benzoic acid (CAS 1208083-20-8)
- 4-Hydroxy-3,5-dimethoxybenzonitrile (CAS 72684-95-8)
- (8-Isopropyl-8-azabicyclo[3.2.1]octan-3-yl)methanamine (CAS 1209593-91-8)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-indole (CAS 690632-17-8)
- 1187167-14-1 4-(3,4-Dimethylbenzoyl)isoquinoline MFCD13153073 (CAS 1187167-14-1)
- 2-(1-Methyl-piperidin-4-ylmethoxy)-ethylamine (CAS 1353971-78-4)
- N-((5-Bromofuran-2-yl)methylene)-1-phenylmethanamine (CAS 212117-18-5)
- (1H-Imidazol-4-yl)(p-tolyl)methanone (CAS 78892-77-0)
- Semaglutide Impurity 1(OtBu-Ste-D-γGlu(OtBu)-AEEA-AEEA-OH) (CAS CATO-C4X-22261)
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