7-Chloro-3-hydroxy-2-phenyl-3,4-dihydroquinazolin-4-one CAS 477864-75-8
| CAS No. | 477864-75-8 |
| Molecular Formula | C14H9ClN2O2 |
| Molecular Weight | 272.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Chloro-3-hydroxy-2-phenyl-3,4-dihydroquinazolin-4-one (C14H9ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
7-Chloro-3-hydroxy-2-phenyl-3,4-dihydroquinazolin-4-one (CAS 477864-75-8), molecular formula C14H9ClN2O2 and molecular weight 272.69 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-Chloro-3-hydroxy-2-phenyl-3,4-dihydroquinazolin-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9ClN2O2 |
| Molecular Weight | 272.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 6-chloro-3-hydroxy-2-phenylquinazolin-4(3H)-one (CAS 100527-73-9)
- 2-(5-Chloro-2-hydroxyphenyl)quinazolin-4(3H)-one (CAS 1151-84-4)
- 5-Chloro-3-(3-phenoxyphenyl)-1,2,4-oxadiazole (CAS 1183803-32-8)
- 3-chloro-4-(1H-indazol-1-yl)benzoic acid (CAS 1283004-89-6)
- 1-Chloro-5-hydrazinylanthracene-9,10-dione (CAS 261962-07-6)
- 2-(2-Chloro-4-nitrophenyl)-2-phenylacetonitrile (CAS 83783-67-9)
- 2-(4-Chloro-2-nitrophenyl)-1H-indole (CAS 65287-40-3)
- 2-(4-Chloro-3-nitrophenyl)-1H-indole (CAS 918482-41-4)
Recommended Standards
- 7-(3-Chloro-2-hydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione (CAS 3880-32-8)
- 7-Chloro-4-nitro-2-phenyl-1H-indole (CAS 663177-42-2)
- 6-Chloro-2-phenylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 220465-51-0)
- 9-Chloro-3-methyl-5-nitroacridine (CAS 255713-06-5)
- 2,2,2-trifluoroethyl N-(2,2,2-trifluoroethyl)carbamate (CAS 1221722-29-7)
- 1-[3-bromo-4-(4-fluoro-2,6-dimethyl-phenoxy)phenyl]ethanone (CAS 2138863-82-6)
- 4-(1H-Indol-4-yl)but-3-en-2-one (CAS 74068-98-7)
- Ethyl 5-(((2-bromophenyl)thio)methyl)isoxazole-3-carboxylate (CAS 823219-94-9)
- 4-(2-Amino-1-(1h-indol-3-yl)ethyl)-N,N-dimethylaniline hydrochloride (CAS 1171502-49-0)
- 1-(1-(Pyridin-4-yl)butyl)-1H-indol-5-ol (CAS 141101-98-6)
- 2-(Ethylamino)-3-(4-iodo-1h-pyrazol-1-yl)-2-methylpropanamide (CAS 1343167-63-4)
- 3-(4-Methylthiazol-2-yl)-2-oxo-2H-chromen-7-yl 4-chlorobutanoate (CAS 637747-73-0)
- 5-(3-Methoxybenzyl)thiazol-2-amine hydrochloride (CAS 2095411-13-3)
- endo-Arg30-Semaglutide (CAS CATO-C4X-2226281)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com