Ethyl 5-cyano-6-[4-(2-fluorophenyl)piperazin-1-yl]-2-phenylpyridine-3-carboxylate CAS 477866-17-4
| CAS No. | 477866-17-4 |
| Molecular Formula | C25H23FN4O2 |
| Molecular Weight | 430.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ethyl 5-cyano-6-[4-(2-fluorophenyl)piperazin-1-yl]-2-phenylpyridine-3-carboxylate (C25H23FN4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Ethyl 5-cyano-6-[4-(2-fluorophenyl)piperazin-1-yl]-2-phenylpyridine-3-carboxylate (CAS 477866-17-4), a certified reference material (molecular formula C25H23FN4O2, MW 430.47 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 5-cyano-6-[4-(2-fluorophenyl)piperazin-1-yl]-2-phenylpyridine-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H23FN4O2 |
| Molecular Weight | 430.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Ethyl Standards
- N-(4-Cyano[1,1-biphenyl]-4-yl)-N-[4-(3H-imidazo[4,5-β]pyridin-7-yl)phenyl] Urea (CAS 1361414-26-7)
- 2-((3-Cyano-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)-N-(3-cyanophenyl)acetamide (CAS 626228-76-0)
- 2-[(4-Cyano-5-methyl-1,2-thiazol-3-yl)sulfanyl]-N'-[2-(2,4-dichlorophenoxy)ethanimidoyl]acetohydrazide (CAS 338395-70-3)
- Ethyl 2-(2-((3-cyano-4,6-dimethylpyridin-2-yl)thio)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 333778-29-3)
- 2-[(4-Cyano-5-methyl-1,2-thiazol-3-yl)sulfanyl]-N'-{2-[3-(trifluoromethyl)phenoxy]ethanimidoyl}acetohydrazide (CAS 338418-56-7)
- 1-(4-Cyano-2-(4-(N,N-diethylsulfamoyl)phenyl)oxazol-5-yl)piperidine-4-carboxamide (CAS 941243-13-6)
- N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-2-((5-cyano-[2,3'-bipyridin]-6-yl)thio)acetamide (CAS 445383-46-0)
- N-(1-Cyano-1-cyclopropylethyl)-2-((4-(3,4-dimethylphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 732997-05-6)
Recommended Standards
- 1-(2-Bromo-5-fluorobenzyl)-4-(2-((tert-butyldimethylsilyl)oxy)ethyl)piperidine (CAS 1704065-55-3)
- Nafcillin Sulfoxide (CAS 41061-20-5)
- Ez,z)-2-(2-benzyloxycarbonylamino-4-thiazol)-4-(3-methyl-2-butenyloxycarbonyl)-2-butenoicacid (CAS 155657-19-5)
- N-Cyclopentyl-5-(4-fluorobenzyl)-3-oxo-2-phenyl-3,5-dihydro-2H-pyrazolo[4,3-c]pyridine-7-carboxamide (CAS 921550-99-4)
- 4-[(butan-2-yl)amino]-3-nitrobenzamide (CAS 852385-66-1)
- 6-Hydroxy-3-iodo-[2,2'-bipyridine]-5-carbonitrile (CAS 1092352-61-8)
- 1-((Tetrahydro-2H-pyran-4-yl)methyl)-1H-pyrazole-5-carboxylic acid (CAS 1309785-34-9)
- 4-((2-Chloro-5-nitrobenzylidene)amino)-3-(3-ethoxyphenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 497949-84-5)
- 1,4-Dimethyltetralin, 56% (CAS 4175-54-6)
- 3,4-Dinitrobenzaldehyde (CAS 35998-98-2)
- (R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(2-(trifluoromethyl)phenyl)butanoic acid (CAS 269726-72-9)
- 4-((3-Bromothiophen-2-yl)methyl)thiomorpholine-3,5-dione (CAS 1875850-14-8)
- 1-Methyl-5-thien-2-yl-1H-pyrazole-3-carbonyl chloride (CAS 876316-46-0)
- Semaglutide impurity 227 (CAS CATO-C4X-2226227)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com