2-(3,5-Dimethylphenoxy)-5-(trifluoromethyl)benzonitrile CAS 477867-14-4
| CAS No. | 477867-14-4 |
| Molecular Formula | C16H12F3NO |
| Molecular Weight | 291.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(3,5-Dimethylphenoxy)-5-(trifluoromethyl)benzonitrile.
CATO supplies 2-(3,5-Dimethylphenoxy)-5-(trifluoromethyl)benzonitrile (CAS 477867-14-4), a certified reference material (molecular formula C16H12F3NO, MW 291.27 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-(3,5-Dimethylphenoxy)-5-(trifluoromethyl)benzonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 291.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12F3NO |
| Molecular Weight | 291.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Dimethylphenoxy Standards
- 2-(2,3-Dimethylphenoxy)-5-(trifluoromethyl)benzonitrile (CAS 477867-13-3)
- 2-((2-(3,5-Dimethylphenoxy)ethyl)thio)-6-methylpyrimidin-4(1H)-one (CAS 697237-88-0)
- 4-(2,4-Dimethylphenoxy)-N-(thiazol-2-yl)butanamide (CAS 496036-26-1)
- Methyl 2-(2-((3,5-dimethylphenoxy)methyl)morpholino)acetate (CAS 1706435-31-5)
- Methyl 2-(2-((2,6-dimethylphenoxy)methyl)morpholino)acetate (CAS 1706454-60-5)
- 1-(2-(2,5-Dimethylphenoxy)ethyl)-1H-indole-3-carbaldehyde (CAS 340318-67-4)
- 1-(2-(2,6-Dimethylphenoxy)ethyl)-1H-indole-3-carbaldehyde (CAS 428490-16-8)
- 1-(2-(3,5-Dimethylphenoxy)ethyl)-1H-indole-3-carbaldehyde (CAS 884497-57-8)
Recommended Standards
- 2-(4-(Trifluoromethyl)phenyl)-2,3-dihydroquinolin-4(1H)-one (CAS 946049-56-5)
- 1-Methyl-N-(2-(trifluoromethyl)phenyl)-1H-benzo[d]imidazol-2-amine (CAS 630092-11-4)
- 2-(Furan-2-yl)-5-methyl-1-(3-(trifluoromethyl)phenyl)-1H-pyrrole (CAS 338963-33-0)
- 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl cyclohexylcarbamate (CAS 477713-71-6)
- 2-(Allyloxy)-5-chlorobenzoic acid (CAS 62176-22-1)
- 2-(3-(5-Phenyl-2h-tetrazol-2-yl)adamantan-1-yl)acetic acid (CAS 438221-39-7)
- 2-(Difluoromethyl)-4-hydroxy-6-iodo-3-methoxypyridine (CAS 1807160-99-1)
- 2-Methyl-2-(3-(trifluoromethyl)phenyl)propanoic acid (CAS 254895-42-6)
- 2-Fluoro-4-(4-methoxyphenyl)benzonitrile (CAS 123864-93-7)
- 2-Methyl-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS 2382-08-3)
- 3-Bromo-2-fluoro-4-methylphenylboronic acid (CAS 2377608-04-1)
- 2,5-Difluoro-3-hydroxybenzonitrile (CAS 1806367-92-9)
- 5-ethoxy-1,3-benzothiazol-2-amine (CAS 70066-70-5)
- Biotinyl-Glucagon (1-29) (human, rat, porcine) trifluoroacetate salt (CAS 1802086-28-7)
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