6-(((4-Chlorophenyl)thio)methyl)-N-methyl-2-phenylpyrimidin-4-amine CAS 477867-15-5
| CAS No. | 477867-15-5 |
| Molecular Formula | C18H16ClN3S |
| Molecular Weight | 341.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-(((4-Chlorophenyl)thio)methyl)-N-methyl-2-phenylpyrimidin-4-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-(((4-Chlorophenyl)thio)methyl)-N-methyl-2-phenylpyrimidin-4-amine (CAS 477867-15-5) is a high-purity analytical reference standard with the molecular formula C18H16ClN3S and a molecular weight of 341.86 g/mol.
The molecular framework of 6-(((4-Chlorophenyl)thio)methyl)-N-methyl-2-phenylpyrimidin-4-amine (C18H16ClN3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H16ClN3S |
| Molecular Weight | 341.86 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 2-(2-((4-Chlorophenyl)thio)acetyl)-N-cyclohexylhydrazine-1-carboxamide (CAS 331459-74-6)
- (4-Chlorophenyl)(5-(dimethylamino)-4-phenylthiophen-2-yl)methanone (CAS 338976-03-7)
- 1-(2-{[(4-chlorophenyl)methyl]sulfanyl}-4-methylquinolin-3-yl)ethan-1-one (CAS 400074-54-6)
- 1-(4-Chlorophenyl)-3-((4-cyclohexylphenyl)amino)propan-1-one (CAS 882748-68-7)
- 3-((4-Chlorophenyl)(phenyl)methoxy)-8-methyl-8-azabicyclo[3.2.1]octane (CAS 5627-46-3)
- 1-(2-Chlorophenyl)-N-cyclopropyl-N-(thiophen-3-ylmethyl)methanesulfonamide (CAS 1235229-12-5)
- 1-((2-Chlorophenyl)sulfonyl)-4-(thiophen-3-yl)piperidine (CAS 1396749-63-5)
- 4-(4-Chlorophenyl)-5-(ethylsulfonyl)-1H-thieno[2,3-c]pyrazol-3-amine (CAS 1707668-34-5)
Recommended Standards
- 4-Chloro-N-((4-morpholinophenyl)carbamothioyl)butanamide (CAS 637303-35-6)
- 6-((4-Chlorobenzyl)thio)-3,4-dihydro-2H-1,4-ethano-1,5-naphthyridine-7-carbonitrile (CAS 889950-49-6)
- 2-(Chloromethyl)-1-ethyl-5-(piperidine-1-sulfonyl)-1h-1,3-benzodiazole (CAS 785792-45-2)
- 5-Chloro-2-(4-(heptyloxy)phenyl)-2H-isoindole (CAS 189884-41-1)
- 4-(Bromomethyl)-1,2-bis[(tert-butyldimethylsilyl)oxy]benzene (CAS 161688-42-2)
- 2-Chloro-1-[4-(3-methylpiperidine-1-carbonyl)piperidin-1-yl]ethan-1-one (CAS 1306606-87-0)
- (3-Iodo-4-(trifluoromethyl)phenyl)methanol (CAS 372120-52-0)
- 2-[(Diphenylmethyl)amino]acetic acid (CAS 40718-29-4)
- 4-Nitrophenyl 2-(2-tert-butoxy-2-oxoethyl)-2-methylhydrazinecarboxylate (CAS 1398504-08-9)
- tert-Butyl ((1-(2-chloronicotinoyl)piperidin-3-yl)methyl)carbamate (CAS 1353974-41-0)
- 2,5,6-Trichloro-4-methylnicotinic acid (CAS 294876-53-2)
- 3-Amino-5-chlorobenzofuran-2-carbonitrile (CAS 887281-48-3)
- tert-Butyl N-[(3S,4R)-3-methoxypiperidin-4-yl]carbamate (CAS 1000027-16-6)
- 263251-78-1 NMG938VJ6T D-3 Tavilermide [USAN:INN] UNII-NMG938VJ6T MIM-D3 MIM-D 3 D 3 (peptide) Tavilermide (CAS 263251-78-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com