4-Fluoro-N-{2-[({5-oxo-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-3-yl}methyl)sulfanyl]phenyl}benzamide CAS 477868-79-4
| CAS No. | 477868-79-4 |
| Molecular Formula | C24H18FN3O2S2 |
| Molecular Weight | 463.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 4-Fluoro-N-{2-[({5-oxo-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-3-yl}methyl)sulfanyl]phenyl}benzamide (CAS 477868-79-4), a certified reference material (molecular formula C24H18FN3O2S2, MW 463.55 g/mol) for analytical method development and quality control.
The molecular framework of 4-Fluoro-N-{2-[({5-oxo-2H,3H,5H-[1,3]thiazolo[2,3-b]quinazolin-3-yl}methyl)sulfanyl]phenyl}benzamide (C24H18FN3O2S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H18FN3O2S2 |
| Molecular Weight | 463.55 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Fluoro Standards
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Recommended Standards
- 4-(4-Butoxybenzoyl)-3-hydroxy-1-(5-methyl-1,3,4-thiadiazol-2-yl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one (CAS 609795-42-8)
- 5- (CAS 326496-05-3)
- 2,2',2''-(10-(2-((2-Mercaptoethyl)amino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid (CAS 865470-67-3)
- N-(3,4-dichlorophenyl)-2-((2,4,5-trichlorophenyl)sulfonyl)hydrazine-1-carboxamide (CAS 706772-78-3)
- (2R)-1-(2,5-Difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one (CAS 241479-69-6)
- 5-Amino-N-(3,5-dimethoxyphenyl)-1-(p-tolyl)-1H-1,2,3-triazole-4-carboxamide (CAS 1260987-50-5)
- (3R)-3-amino-3-(4-fluorophenyl)propanamide hydrochloride (CAS 1384424-47-8)
- Potassium Sucrose Octasulfate (CAS 76578-81-9)
- 4-(Chloromethyl)-1-cyclohexyl-2-(trifluoromethyl)benzene (CAS 957205-24-2)
- 2-(((3-Bromothiophen-2-yl)methyl)amino)-2-methylpropan-1-ol (CAS 1250923-26-2)
- METHACHOLINE CHLORIDE (CAS 62-51-1)
- 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)propan-1-ol (CAS 1040006-07-2)
- 6-Chloro-N-(cyclopent-3-en-1-yl)-2-methylpyrimidin-4-amine (CAS 1394733-07-3)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
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