3-Fluoro-5-methoxy-N-(2-(3-(piperazin-1-ylmethyl)-imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide CAS 925437-64-5
| CAS No. | 925437-64-5 |
| Molecular Formula | C24H24FN5O2S |
| Molecular Weight | 465.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Fluoro-5-methoxy-N-(2-(3-(piperazin-1-ylmethyl)-imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide (CAS 925437-64-5), molecular formula C24H24FN5O2S and molecular weight 465.54 g/mol, is a CATO reference standard with documented purity and traceability.
3-Fluoro-5-methoxy-N-(2-(3-(piperazin-1-ylmethyl)-imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide (C24H24FN5O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Fluoro-5-methoxy-N-(2-(3-(piperazin-1-ylmethyl)-imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H24FN5O2S |
| Molecular Weight | 465.54 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 3-(4'-Hydroxy-[1,1'-biphenyl]-4-yl)-N-(trans-4-hydroxycyclohexyl)-1,4-dihydroindeno[1,2-c]pyrazole-6-carboxamide (CAS 760990-15-6)
- Fmoc-N-Me-u(OtBu)-OH (CAS 72156-62-8)
- 2-((5-(Dimethylcarbamoyl)-3-(ethoxycarbonyl)-4-methylthiophen-2-yl)amino)-2-oxoethyl 2-(methylthio)nicotinate (CAS 742118-59-8)
- Ku 0063794 (CAS 938440-64-3)
- 2-Fluoro-2-(oxetan-3-yl)acetic acid (CAS 1779934-83-6)
- 3-[(3-nitro-1h-pyrazol-1-yl)methoxy]benzaldehyde (CAS 1006435-82-0)
- (E)-4-Hydroxy Hexenal (CAS 17427-21-3)
- (2,4-Difluoro-5-formylphenyl)boronic acid (CAS 1413393-42-6)
- (R/S)-N-Deacetyl Colchicine (CAS 102491-73-6)
- 2-(1-fluorovinyl)pyridine (CAS 1331912-48-1)
- 3-(4-Ethyl-3-methyl-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)-4-methylbenzoic acid (CAS 1015844-33-3)
- 6-Propoxypicolinic acid (CAS 1249545-27-4)
- (R)-Methyl 2-(((benzyloxy)carbonyl)amino)-2-(4-oxocyclohexyl)acetate (CAS 1384268-84-1)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
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