1-(3-Chlorophenyl)-4-({4-[(4-methylphenyl)sulfanyl]-3-nitrophenyl}methyl)piperazine CAS 477869-33-3
| CAS No. | 477869-33-3 |
| Molecular Formula | C24H24ClN3O2S |
| Molecular Weight | 453.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3-Chlorophenyl)-4-({4-[(4-methylphenyl)sulfanyl]-3-nitrophenyl}methyl)piperazine.
CATO supplies 1-(3-Chlorophenyl)-4-({4-[(4-methylphenyl)sulfanyl]-3-nitrophenyl}methyl)piperazine (CAS 477869-33-3), a certified reference material (molecular formula C24H24ClN3O2S, MW 453.98 g/mol) for analytical method development and quality control.
Structurally, 1-(3-Chlorophenyl)-4-({4-[(4-methylphenyl)sulfanyl]-3-nitrophenyl}methyl)piperazine (C24H24ClN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 453.98 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H24ClN3O2S |
| Molecular Weight | 453.98 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 1-Benzyl-4-({4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}methyl)piperazine (CAS 477869-39-9)
- 4-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-6-[(4-fluorophenyl)sulfanyl]-2-(pyridin-2-yl)pyrimidine (CAS 338961-01-6)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)acetamide (CAS 763095-00-7)
- (Z)-2-((4-chlorophenyl)thio)-1-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)ethan-1-one O-(4-fluorobenzyl) oxime (CAS 478047-79-9)
- N-(4-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)-3-fluorophenyl)-3-methylbutanamide (CAS 866131-35-3)
- (E)-{[4-(4-chlorophenyl)-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5-trien-3-yl]methylidene}amino 4-fluorobenzoate (CAS 478041-89-3)
- N-[(2-Chlorophenyl)methyl]-2-{[3-cyano-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinolin-2-yl]sulfanyl}acetamide (CAS 626228-72-6)
- (E)-({5-[(4-chlorophenyl)sulfanyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl}methylidene)amino 4-methylbenzoate (CAS 321553-44-0)
Recommended Standards
- 2'-(4-(3-Chlorothiophen-2-yl)thiazol-2-yl)-5,5'-dimethyl-2-phenyl-1',2'-dihydro-2H,3'H-[3,4'-bipyrazol]-3'-one (CAS 321385-48-2)
- Loratadine Impurity 57 (CAS CATO-C4X-142657)
- N-{4-[4-(4-chlorobenzenesulfonyl)piperazin-1-yl]-3-fluorophenyl}pentanamide (CAS 478079-26-4)
- 4-Chloro-N-(2,5,6-trimethyl-1-(3-methylbenzyl)-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338964-20-8)
- Methyl α-D-Glucoside (CAS 97-30-3)
- 6-(Hydroxy(methyl)amino)-9H-purin-2-amine (CAS 60254-49-1)
- 3-Amino-5-mercapto-1,2,4-triazole (CAS 16691-43-3)
- (S)-Benzyl (1-bromopropan-2-yl)carbamate (CAS 53843-95-1)
- 6-(Methoxymethoxy)naphthalene-2-boronic acid (CAS 2246782-98-7)
- 2-((4-Chlorophthalazin-1-yl)amino)ethan-1-ol (CAS 98911-72-9)
- 2-((2-Cyano-3-methylbutan-2-yl)amino)-2-oxoethyl 4-((2-oxopyrrolidin-1-yl)methyl)benzoate (CAS 871672-87-6)
- Mesityl(piperazin-1-yl)methanone (CAS 1016695-42-3)
- 7-Methoxy-4-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid (CAS 20940-76-5)
- SV40 Nuclear Transport Signal Peptide Analog (CAS 104914-40-1)
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