Loratadine Impurity 57 CAS CATO-C4X-142657
| CAS No. | CATO-C4X-142657 |
| Molecular Formula | C25H28ClN3O3 |
| Molecular Weight | 453.96 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Loratadine Impurity 57 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Loratadine Impurity 57 (CAS CATO-C4X-142657) is a certified pharmaceutical impurity reference standard with the molecular formula C25H28ClN3O3 and a molecular weight of 453.96 g/mol.
Based on its molecular formula C25H28ClN3O3, Loratadine Impurity 57 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 453.96 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C25H28ClN3O3 |
| Molecular Weight | 453.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Loratadine Standards
- Loratadine Impurity 45 (CAS CATO-C4X-142645)
- Loratadine Impurity 59 (CAS CATO-C4X-142659)
- Loratadine Impurity 47 (CAS CATO-C4X-142647)
- Loratadine Impurity 25 (CAS CATO-C4X-142625)
- Loratadine Impurity 82 (CAS CATO-C4X-142682)
- Loratadine Impurity 100 (CAS CATO-C4X-1426100)
- Loratadine Impurity 63 (CAS CATO-C4X-142663)
- Loratadine Impurity 61 (CAS CATO-C4X-142661)
Recommended Standards
- N-{4-[4-(4-chlorobenzenesulfonyl)piperazin-1-yl]-3-fluorophenyl}pentanamide (CAS 478079-26-4)
- 2'-(4-(3-Chlorothiophen-2-yl)thiazol-2-yl)-5,5'-dimethyl-2-phenyl-1',2'-dihydro-2H,3'H-[3,4'-bipyrazol]-3'-one (CAS 321385-48-2)
- N-(4-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)-3-fluorophenyl)-3-methylbutanamide (CAS 866131-35-3)
- 1-(3-Chlorophenyl)-4-({4-[(4-methylphenyl)sulfanyl]-3-nitrophenyl}methyl)piperazine (CAS 477869-33-3)
- Fospropofol impurity 6 (CAS CATO-C4X-31516)
- Nicotinic Acid EP Impurity B (CAS 1802-30-8)
- Erythromycin Sulfonamide Impurity B Oxime Derivative (CAS 231620-64-7)
- 4-Bromo-2,2-dimethylindolin-3-one (CAS 2761573-12-8)
- 4-Iodobenzene-1,2-diol (CAS 76149-14-9)
- (2R,4'R,8a'R)-1-tert-butyl 4'-methyl 6'-oxohexahydrospiro[pyrrolidine-2,7'-pyrrolo[2,1-b][1,3]thiazine]-1,4'-dicarboxylate (CAS 221040-37-5)
- (R)-1-Benzyl-5-oxopyrrolidine-3-carboxylicacid (CAS 1217736-39-4)
- N-methyl-2-(pyrrolidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-2-amine (CAS 885951-06-4)
- 5-Chloro-6-fluoro-2-methyl-1H-benzo[d]imidazole (CAS 871223-81-3)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
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