4-[(Z)-2-(2,4-Dichlorophenyl)ethenyl]-2-(3-fluoro-4-iodophenyl)pyrimidine CAS 477870-85-2
| CAS No. | 477870-85-2 |
| Molecular Formula | C18H10Cl2FIN2 |
| Molecular Weight | 471.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-[(Z)-2-(2,4-Dichlorophenyl)ethenyl]-2-(3-fluoro-4-iodophenyl)pyrimidine (CAS 477870-85-2), a certified reference material (molecular formula C18H10Cl2FIN2, MW 471.09 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/iodine substitution, 4-[(Z)-2-(2,4-Dichlorophenyl)ethenyl]-2-(3-fluoro-4-iodophenyl)pyrimidine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 471.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H10Cl2FIN2 |
| Molecular Weight | 471.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Z Standards
- 5-(2,4-Dichlorophenyl)-3-(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)-4,6-dioxo-octahydropyrrolo[3,4-c]pyrrole-1-carboxylic acid (CAS 321521-99-7)
- 5-(3,4-Dichlorophenyl)-4-(3-fluoro-4-methylbenzoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618076-11-2)
- N-(3,4-Dichlorophenyl)-2-((5-(4-hydroxyphenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332881-74-0)
- 7-(3,4-Dichlorophenyl)-2-[4-(3-methylphenyl)piperazin-1-yl]-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1251646-25-9)
- 5-(3,4-Dichlorophenyl)-4-(methylsulfonyl)-1-(2,3,4-trichlorophenyl)-1H-pyrazole (CAS 400088-12-2)
- 5-(3,4-Dichlorophenyl)-4-(methylsulfonyl)-1-(2,4,6-trichlorophenyl)-1H-pyrazole (CAS 321574-34-9)
- N-(2,4-Dichlorophenyl)-2-((5-(pyridin-4-yl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477318-67-5)
- N-(2,6-Dichlorophenyl)-2-((5-(pyridin-4-yl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477318-71-1)
Recommended Standards
- Chlorhexidine EP Impurity M (CAS 152504-12-6)
- N,N-bis(2-chloro-6-fluorobenzyl)-N-({[(2,2-dichloroethanimidoyl)amino]carbonyl}oxy)amine (CAS 680580-15-8)
- Brexpiprazole Impurity 97 (CAS CATO-C4X-113197)
- 5-tert-Butoxy-5-oxo-2-(4,5,6,7-tetrachloro-1,3-dioxo-isoindolin-2-yl)pentanoic acid (CAS 2227107-17-5)
- 3-(4-Aminophenyl)prop-2-yn-1-ol (CAS 253167-82-7)
- 8a-(4-Chlorophenyl)-octahydropyrrolo[1,2-a]pyrimidin-6-one (CAS 6029-26-1)
- 2,4-Dibromo-1-methoxynaphthalene (CAS 28768-94-7)
- 2,5-bis(octyloxy)terephthalaldehyde (CAS 123440-34-6)
- 2Z,6Z-Farnesol (CAS 16106-95-9)
- 3-Chloro-6,7-dihydro-5H-cyclopenta[b]pyridin-7-ol (CAS 1357097-05-2)
- 1-(2-Methyl-3-(trifluoromethyl)phenyl)ethan-1-one (CAS 1017778-01-6)
- 3-(2,3-Dihydrobenzofuran-5-yl)isoxazol-5-amine (CAS 1250709-84-2)
- 4-Amino-3,4-dimethylpentanoic acid (CAS 19449-93-5)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
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