(E)-1-(4-((2-chloro-6-fluorobenzyl)oxy)phenyl)-3-(dimethylamino)prop-2-en-1-one CAS 477871-12-8
| CAS No. | 477871-12-8 |
| Molecular Formula | C18H17ClFNO2 |
| Molecular Weight | 333.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(E)-1-(4-((2-chloro-6-fluorobenzyl)oxy)phenyl)-3-(dimethylamino)prop-2-en-1-one (CAS 477871-12-8), molecular formula C18H17ClFNO2 and molecular weight 333.78 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (E)-1-(4-((2-chloro-6-fluorobenzyl)oxy)phenyl)-3-(dimethylamino)prop-2-en-1-one (C18H17ClFNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 333.78 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures (E)-1-(4-((2-chloro-6-fluorobenzyl)oxy)phenyl)-3-(dimethylamino)prop-2-en-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17ClFNO2 |
| Molecular Weight | 333.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- 2-(3-Chloro-4-fluorophenyl)-4,4-dimethyl-1,2,3,4-tetrahydroquinoline-6-carboxylic acid (CAS 1353971-43-3)
- (2-Chloro-4-fluorophenyl)(3-(morpholinomethyl)phenyl)methanone (CAS 898792-07-9)
- (3-Chloro-4-fluorophenyl)(3-(morpholinomethyl)phenyl)methanone (CAS 898791-86-1)
- (3-Chloro-5-fluorophenyl)(2-(morpholinomethyl)phenyl)methanone (CAS 898750-92-0)
- (3-Chloro-5-fluorophenyl)(3-(morpholinomethyl)phenyl)methanone (CAS 898792-10-4)
- (4-Chloro-3-fluorophenyl)(3-(morpholinomethyl)phenyl)methanone (CAS 898791-83-8)
- 2-Chloro-4-fluoro-2-morpholinomethyl benzophenone (CAS 898750-89-5)
- 2-Chloro-4-fluoro-4-morpholinomethyl benzophenone (CAS 898770-47-3)
Recommended Standards
- (E)-3-((4-chlorophenyl)amino)-1-(4-(3-fluoropropoxy)phenyl)prop-2-en-1-one (CAS 477889-20-6)
- 3-Chloro-4-fluoro-2-morpholinomethyl benzophenone (CAS 898750-68-0)
- 3-Chloro-4-fluoro-4-morpholinomethyl benzophenone (CAS 898770-26-8)
- 3-Chloro-5-fluoro-4-morpholinomethyl benzophenone (CAS 898770-50-8)
- 3-(4-Amino-5-methyl-1h-pyrazol-1-yl)tetrahydrothiophene 1,1-dioxide (CAS 1251362-57-8)
- 4-Oxo-N-((5-phenylisoxazol-3-yl)methyl)-4H-chromene-2-carboxamide (CAS 946344-30-5)
- 2-(4-(5-Bromopyrimidin-2-yl)piperazin-1-yl)acetonitrile (CAS 1252167-02-4)
- 4,8-Diamino-1,2,5,6-tetrahydroxy-9,10-anthracenedione (CAS 6370-88-3)
- 1h-Pyrazole-4-carbothioamide (CAS 1017781-31-5)
- 2-(5-Chloropyridin-3-yl)propan-2-ol (CAS 412016-75-2)
- 1-(Fluoromethyl)-5-methyl-1H-pyrrole-2-carbonitrile (CAS 463298-07-9)
- 1-(2-Fluorophenyl)-4-(3-isopropyl-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one (CAS 1172520-68-1)
- 2-Fluoro-5-methoxy-3-(trifluoromethyl)-benzoyl chloride (CAS 1373920-78-5)
- C-Peptide 2 (rat) (CAS 41594-08-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com