N-(4-chloro-2-methylphenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide CAS 477872-23-4
| CAS No. | 477872-23-4 |
| Molecular Formula | C21H16ClN3O3S |
| Molecular Weight | 425.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 425.89 g/mol gives N-(4-chloro-2-methylphenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies N-(4-chloro-2-methylphenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide (CAS 477872-23-4), a certified reference material (molecular formula C21H16ClN3O3S, MW 425.89 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, N-(4-chloro-2-methylphenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 425.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-chloro-2-methylphenyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H16ClN3O3S |
| Molecular Weight | 425.89 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- 1-(3-Chloro-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl)-N-(pyridin-2-ylmethyl)methanesulfonamide (CAS 1001917-35-6)
- N-(3-Chloro-4-methoxyphenyl)-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105235-07-1)
- (2-(4-Chloro-2-methylphenoxy)pyridin-3-yl)(4-(2-fluorophenyl)piperazin-1-yl)methanone (CAS 497060-65-8)
- 1-(4-Chloro-2-methylphenyl)-3-(1-((4-fluorophenyl)sulfonyl)piperidin-4-yl)urea (CAS 672950-46-8)
- 2-((3-Chloro-4-fluorophenyl)amino)-N-(4-(piperidin-1-ylsulfonyl)phenyl)acetamide (CAS 853695-44-0)
- 4-Chloro-N'-(1-(3-fluorobenzyl)piperidine-4-carbonyl)benzenesulfonohydrazide (CAS 478259-18-6)
- Ethyl 1-(2-(3-(3-chloro-4-methoxyphenyl)ureido)-2-methylpropanoyl)piperidine-4-carboxylate (CAS 1439375-03-7)
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Recommended Standards
- N-(5-(3-(2-Chlorophenyl)acryloyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)pyrazine-2-carboxamide (CAS 1351663-87-0)
- 2-(Difluoromethyl)-4,5-diiodo-3-nitropyridine (CAS 1803704-46-2)
- 2-(Difluoromethyl)-3,4-diiodo-5-nitropyridine (CAS 1806825-03-5)
- 2-(Difluoromethyl)-4,6-diiodo-3-nitropyridine (CAS 1806893-37-7)
- 1-(2-aminoethyl)azepan-2-one hydrochloride (CAS 72649-25-3)
- N,6-Dimethyl-5-(1-methylpyrrolidin-2-yl)pyridin-2-amine (CAS 1352492-93-3)
- ethyl 3-(hydroxymethyl)-1-methyl-1H-pyrazole-5-carboxylate (CAS 199480-28-9)
- Ethyl 4-iodo-3-nitrobenzoate (CAS 57362-77-3)
- 1-(2-Fluoro-4-iodophenyl)piperazine (CAS 1121613-61-3)
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- Carbamazepine 10,11-Epoxide-d2 (Major) (CAS 1185025-41-5)
- 3-(1,3-Dioxolan-2-yl)-3-methylbenzophenone (CAS 898778-83-1)
- Ethyl 2-(4-cyanophenyl)-2-(phenylamino)acetate (CAS 40577-15-9)
- D-Asp9-Tirzepatide (CAS CATO-CPTD788923)
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