(E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino N-(3-chlorophenyl)carbamate CAS 477872-53-0
| CAS No. | 477872-53-0 |
| Molecular Formula | C19H15Cl2N3O2S |
| Molecular Weight | 420.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino N-(3-chlorophenyl)carbamate (CAS 477872-53-0), molecular formula C19H15Cl2N3O2S and molecular weight 420.31 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino N-(3-chlorophenyl)carbamate (C19H15Cl2N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H15Cl2N3O2S |
| Molecular Weight | 420.31 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related E Standards
- (E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino N-(4-chlorophenyl)carbamate (CAS 477872-51-8)
- 6-(3-Chlorophenyl)-5-(4-hexyl-3-propylphenyl)picolinaldehyde (CAS 1350436-46-2)
- 3-(4-Chlorophenyl)-5-((2,5-dimethylbenzyl)thio)-4-(p-tolyl)-4H-1,2,4-triazole (CAS 477330-28-2)
- 6-{[(4-chlorophenyl)sulfanyl]methyl}-2-{[(4-fluorophenyl)methyl]sulfanyl}-N,N-dimethylpyrimidin-4-amine (CAS 341965-50-2)
- 5-(3-(4-(4-Chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one (CAS 1380392-05-1)
- (Z)-[(4-Chlorophenyl)methoxy][1-phenyl-2-(4-phenylpiperazin-1-yl)ethylidene]amine (CAS 250714-03-5)
- 1-(4-Chlorophenyl)-3-({2',3'-dihydrospiro[adamantane-2,1'-indene]-3'-ylidene}amino)urea (CAS 400083-53-6)
- 6-(3-Chlorophenyl)-2-[3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidin-7-amine (CAS 383147-74-8)
Recommended Standards
- (E)-[1-(4-Methyl-2-phenyl-1,3-thiazol-5-yl)ethylidene]amino N-(2,4-dichlorophenyl)carbamate (CAS 477858-14-3)
- Methyl 3-iodo-4-(isopropylsulfonyl)-5-(methylthio)thiophene-2-carboxylate (CAS 175202-13-8)
- 1,1,1-Trifluoro-N-((1S,2S)-2-(phenylselanyl)-2,3-dihydro-1H-inden-1-yl)methanesulfonamide (CAS 2088566-77-0)
- 1,3-Bis(1,1-dimethylethyl) 2-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]imidodicarbonate (CAS 1391926-49-0)
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- (5Z)-5-[(5-Methylfuran-2-yl)methylidene]-1,3-thiazolidine-2,4-dione (CAS 1218991-77-5)
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- 1,3-Dibromo-2-methylpropene (E/Z Mixture) (CAS 35911-17-2)
- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
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