6-(3-Chlorophenyl)-2-[3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidin-7-amine CAS 383147-74-8
| CAS No. | 383147-74-8 |
| Molecular Formula | C22H18ClN5S |
| Molecular Weight | 419.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-(3-Chlorophenyl)-2-[3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidin-7-amine (C22H18ClN5S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 6-(3-Chlorophenyl)-2-[3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidin-7-amine (CAS 383147-74-8), a certified reference material (molecular formula C22H18ClN5S, MW 419.93 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-(3-Chlorophenyl)-2-[3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl]pyrazolo[1,5-a]pyrimidin-7-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H18ClN5S |
| Molecular Weight | 419.93 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 6-(4-Chlorophenyl)-2-(3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 691869-95-1)
- (3-((4-Chlorophenyl)sulfonyl)azetidin-1-yl)(4-phenyltetrahydro-2H-pyran-4-yl)methanone (CAS 1448056-30-1)
- 4-(4-Chlorophenyl)-1-[3-[2-(4-fluorophenyl)-1,3-dioxolan-2-yl]propyl]-4-piperidinol (CAS 56660-99-2)
- N-(2-(5-(2-Chlorophenyl)-1-isobutyryl-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide (CAS 923250-21-9)
- 5-(3-(4-(4-Chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one (CAS 1380392-05-1)
- (Z)-[(4-Chlorophenyl)methoxy][1-phenyl-2-(4-phenylpiperazin-1-yl)ethylidene]amine (CAS 250714-03-5)
- 1-(4-Chlorophenyl)-3-({2',3'-dihydrospiro[adamantane-2,1'-indene]-3'-ylidene}amino)urea (CAS 400083-53-6)
- 2-(3-Chlorophenyl)-4-(4-methoxyphenyl)-6-(4-methylpiperazin-1-yl)pyrimidine-5-carbonitrile (CAS 477873-09-9)
Recommended Standards
- tert-Butyl (S)-2-((tert-butoxycarbonyl)amino)-3-(3-(chlorosulfonyl)phenyl)propanoate (CAS 2396772-24-8)
- N'-[(1E)-(3-Chlorophenyl)methylidene]-1-(4-methylbenzenesulfonyl)piperidine-4-carbohydrazide (CAS 478030-17-0)
- N-(3-Chloro-2-methylphenyl)-2-((2-phenylquinazolin-4-yl)thio)acetamide (CAS 332914-46-2)
- 2-(Difluoromethyl)-4,6-diiodopyridine-3-acetonitrile (CAS 1805254-12-9)
- N′-(2,6-Difluorophenyl)-N,N-dimethylsulfamide (CAS 866154-28-1)
- 3-(3,4-Dichlorobenzyl)-1,3-thiazinane-2-thione (CAS 866151-56-6)
- 1-Nitro-4-(prop-2-yn-1-yl)benzene (CAS 944896-91-7)
- 4-Chloro-2-isobutyramidobenzoic acid (CAS 405904-57-6)
- 2-(aminomethyl)-3,4-dihydro-2H-1-benzopyran-4-one hydrochloride (CAS 2060063-37-6)
- 2-(3,4-Difluorophenyl)-2-fluoroacetic acid (CAS 915030-47-6)
- 3-Chloro-6-hydrazinyl-[1,2,4]triazolo[4,3-b]pyridazine (CAS 33183-96-9)
- (5-(4-Methoxyphenyl)pyridin-3-yl)boronic acid (CAS 1219737-09-3)
- 2,5-Dichloro-3-nitrobenzenesulfonamide (CAS 36039-00-6)
- Tirzepatide Impurity 59 (CAS CATO-C4X-324059)
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