1-((4-Chlorophenyl)sulfonyl)-N'-(3-(trifluoromethyl)benzoyl)piperidine-4-carbohydrazide CAS 477872-86-9
| CAS No. | 477872-86-9 |
| Molecular Formula | C20H19ClF3N3O4S |
| Molecular Weight | 489.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-((4-Chlorophenyl)sulfonyl)-N'-(3-(trifluoromethyl)benzoyl)piperidine-4-carbohydrazide.
1-((4-Chlorophenyl)sulfonyl)-N'-(3-(trifluoromethyl)benzoyl)piperidine-4-carbohydrazide (CAS 477872-86-9), molecular formula C20H19ClF3N3O4S and molecular weight 489.90 g/mol, is a CATO reference standard with documented purity and traceability.
1-((4-Chlorophenyl)sulfonyl)-N'-(3-(trifluoromethyl)benzoyl)piperidine-4-carbohydrazide (C20H19ClF3N3O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-((4-Chlorophenyl)sulfonyl)-N'-(3-(trifluoromethyl)benzoyl)piperidine-4-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H19ClF3N3O4S |
| Molecular Weight | 489.90 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 1-[(2-Chlorophenyl)methyl]-3-{1-[(2,2-difluoro-2H-1,3-benzodioxol-5-yl)methyl]-2-oxo-1,2-dihydropyridin-3-yl}-1-(propan-2-yl)urea (CAS 400084-69-7)
- (E)-{[4-(4-chlorophenyl)-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5-trien-3-yl]methylidene}({[3-(trifluoromethyl)phenyl]methoxy})amine (CAS 861212-76-2)
- 4-(3-(3-(2-Chlorophenyl)-3-oxopropanoyl)-2-hydroxy-4,6-dimethoxyphenyl)-1-methylpiperidin-3-yl acetate (CAS 244136-25-2)
- 5-[(4-Chlorophenyl)sulfanyl]-4-{[(2,6-dichlorophenyl)methoxy]methyl}-1-methyl-3-phenyl-1H-pyrazole (CAS 321538-27-6)
- 1-[(2-Chlorophenyl)methyl]-3'-(3,4-dichlorophenyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338406-11-4)
- 1-[(3-Chlorophenyl)methyl]-3'-(3,4-dichlorophenyl)-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338406-12-5)
- 3'-(4-Chlorophenyl)-1-[(2,6-dichlorophenyl)methyl]-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 400081-80-3)
- 3'-(4-Chlorophenyl)-1-[(3,4-dichlorophenyl)methyl]-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 477859-00-0)
Recommended Standards
- 2-{2-[(4-methoxyphenyl)formamido]acetamido}ethyl 3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylate (CAS 338419-61-7)
- Indometacin Impurity 43 (CAS CATO-C4X-147043)
- N-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)-4-methoxy-N-(4-methoxyphenyl)benzenesulfonamide (CAS 955975-53-8)
- N'-[(1Z)-{2-[(2-chloro-1,3-thiazol-5-yl)methoxy]naphthalen-1-yl}methylidene]-4-(trifluoromethyl)benzohydrazide (CAS 478064-70-9)
- Mal-Tetra-EG-Osu (CAS 1151762-45-6)
- 2-((3-Methylbutan-2-yl)amino)cyclohexan-1-ol (CAS 1218118-07-0)
- tert-Butyl 4-Aminobenzoate (CAS 18144-47-3)
- [(2R)-Oxetan-2-yl]methanamine (CAS 2090728-35-9)
- 5-Methoxy-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 1219637-79-2)
- Tert-butyl (1-(azetidin-3-yl)ethyl)carbamate hydrochloride (CAS 1379363-25-3)
- 3-(3-Nitrophenyl)-3-(2,2,2-trifluoroacetamido)propanoic acid (CAS 439095-29-1)
- Fenthion-oxon-sulfoxide (CAS 6552-13-2)
- 3-Nitrobenzaldoxime (CAS 3431-62-7)
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