4-(2-Bromo-4-nitrophenoxy)-2-fluoro-1,1'-biphenyl CAS 477888-32-7

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(2-Bromo-4-nitrophenoxy)-2-fluoro-1,1'-biphenyl.

4-(2-Bromo-4-nitrophenoxy)-2-fluoro-1,1'-biphenyl (CAS 477888-32-7) is a high-purity analytical reference standard with the molecular formula C18H11BrFNO3 and a molecular weight of 388.19 g/mol.

4-(2-Bromo-4-nitrophenoxy)-2-fluoro-1,1'-biphenyl (C18H11BrFNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(2-Bromo-4-nitrophenoxy)-2-fluoro-1,1'-biphenyl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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