(2Z)-2-[4-(3-Fluoropropoxy)phenyl]-3-{[4-(trifluoromethoxy)phenyl]amino}prop-2-enenitrile CAS 477888-58-7
| CAS No. | 477888-58-7 |
| Molecular Formula | C19H16F4N2O2 |
| Molecular Weight | 380.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies (2Z)-2-[4-(3-Fluoropropoxy)phenyl]-3-{[4-(trifluoromethoxy)phenyl]amino}prop-2-enenitrile (CAS 477888-58-7), a certified reference material (molecular formula C19H16F4N2O2, MW 380.34 g/mol) for analytical method development and quality control.
(2Z)-2-[4-(3-Fluoropropoxy)phenyl]-3-{[4-(trifluoromethoxy)phenyl]amino}prop-2-enenitrile (C19H16F4N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), (2Z)-2-[4-(3-Fluoropropoxy)phenyl]-3-{[4-(trifluoromethoxy)phenyl]amino}prop-2-enenitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H16F4N2O2 |
| Molecular Weight | 380.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Z Standards
- (E)-3-[4-(3-Fluoropropoxy)phenyl]-N-[2-(3-pyridinyl)-4-pyrimidinyl]-2-propenamide (CAS 478046-38-7)
- (E)-3-[4-(3-Fluoropropoxy)phenyl]-N-[2-(4-pyridinyl)-4-pyrimidinyl]-2-propenamide (CAS 478039-87-1)
- 3-(4-(3-Fluoropropoxy)phenyl)-1-tosyl-1H-pyrazole (CAS 477711-10-7)
- (2Z)-2-[4-(3-Fluoropropoxy)phenyl]-3-[(4-phenoxyphenyl)amino]prop-2-enenitrile (CAS 478039-52-0)
- (E)-1-[4-(3-Fluoropropoxy)phenyl]-3-(4-phenoxyanilino)-2-propen-1-one (CAS 478033-87-3)
- (2Z)-2-[4-(3-Fluoropropoxy)phenyl]-3-{[3-(trifluoromethyl)phenyl]amino}prop-2-enenitrile (CAS 478039-65-5)
- (E)-4-(3-fluoropropoxy)benzaldehyde O-(2,4-dichlorobenzyl) oxime (CAS 477870-63-6)
- (E)-4-(3-fluoropropoxy)benzaldehyde O-(2,6-dichlorobenzyl) oxime (CAS 477870-27-2)
Recommended Standards
- (2S,3R,4S,5R,6R)-2-(((2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-(prop-2-yn-1-yloxy)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 857642-16-1)
- 1-(3-Amino-6-(benzo[d][1,3]dioxol-5-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)ethan-1-one (CAS 626221-00-9)
- Ethyl 2-(1-oxo-6-(((trifluoromethyl)sulfonyl)oxy)-1,2,3,4-tetrahydronaphthalen-2-yl)acetate (CAS 1414797-66-2)
- 1-(4-Fluorobenzyl)-5-oxo-N-(3-(trifluoromethyl)phenyl)pyrrolidine-2-carboxamide (CAS 59749-51-8)
- N-(4-Chlorophenyl)-2,6-dimethylpiperidine-1-carboxamide (CAS 60464-80-4)
- 4-(4-Chloro-2-methylphenyl)-2,2-Dimethyl-4-oxobutyric acid (CAS 951885-42-0)
- 3-(3,4-Dichlorobenzylidene)-5-methyldihydrofuran-2(3H)-one (CAS 93256-69-0)
- 8-Cyclopropyl-8-oxooctanoic acid (CAS 898766-91-1)
- 2,4-dichloro-5,6-dimethylpyrrolo[2,1-f][1,2,4]triazine (CAS 2306273-15-2)
- 4-Ethyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1245642-60-7)
- Rel-(3R,5R)-5-methylpiperidine-3-carboxylic acid (CAS 110287-72-4)
- Tert-butyl 3-cyclopropyl-4-oxopiperidine-1-carboxylate (CAS 1425336-34-0)
- Desfuroyl Ceftiofur (CAS 120882-22-6)
- (Des-Thr7)-Glucagon trifluoroacetate salt (CAS 1802078-28-9)
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